Aptamers are nucleic acid molecules that mimic antibodies by folding into complex 3D
shapes that bind to specific targets. Although some aptamers exist naturally as the ligand …

Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific
targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution …

Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to
bind a wide range of biomedically relevant proteins with affinities and specificities that are …

Systematic evolution of ligand by exponential enrichment (SELEX) is an efficient method
used to isolate high-affinity single stranded oligonucleotides from a large random sequence …

Aptamers are single-stranded nucleic acid molecules that possess properties comparable to
those of protein monoclonal antibodies, and thus are clear alternatives to long established …

Aptamers are a special class of nucleic acid molecules that are beginning to be investigated
for clinical use. These small RNA/DNA molecules can form secondary and tertiary structures …

Today, RNA aptamers are being considered promising theranostic tools against a wide
variety of disorders. RNA aptamers can fold into complex shapes and bind to diverse …

Aptamers, a promising new class of therapeutics, are single-stranded oligonucleotides
generated via an in vitro selection process that bind to and inhibit the activity of target …

Traditional anticancer therapies can cause serious side effects in clinical treatment due to
their nonspecific of tumor cells. Aptamers, also termed as' chemical antibodies', are short …

Systematic evolution of ligands by exponential enrichment (SELEX) has been used to
discover thousands of aptamers since its development in 1990. Aptamers are short single …