According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …

By definition, aging is a natural, gradual and continuous process. On the other hand, frailty
reflects the increase in vulnerability to stressors and shortens the time without disease …

Background Altered intestinal microbiota composition in later life is associated with
inflammaging, declining tissue function, and increased susceptibility to age-associated …

Pneumonia outbreak in the city of Wuhan, China, prompted the finding of a novel strain of
severe acute respiratory syndrome virus (SARS-CoV-2). Here, we discuss potential long …

Abstract Purpose of Review Precision Aging® is a novel concept that we have recently
employed to describe how the model of precision medicine can be used to understand and …

Excess nutrient flux into the cellular energy system results in a scenario of cellular metabolic
stress in diseases involving insulin resistance, such as type 2 diabetes, referred to as nutri …

The direct cause of periodontitis is periodontopathic bacteria, while various environmental
factors affect the severity of periodontitis. Previous epidemiological studies have shown …

Age-related T cell dysfunction contributes to immunosenescence and chronic inflammation.
Aging is also associated with a progressive decline in zinc status. Zinc is an essential …

As people get older, age-related alterations occur that lead to increased susceptibility to
disease. In the current COVID-19 pandemic, older people are particularly susceptible to a …