Pathogenic leptospires are the bacterial agents of leptospirosis, which is an emerging
zoonotic disease that affects animals and humans worldwide. The success of leptospires as …

Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira spp. It is
considered a neglected infectious disease of human and veterinary concern. Our group has …

The mechanisms of disease pathogenesis in leptospirosis are poorly defined. Recent
developments in the application of genetic tools in the study of Leptospira have advanced …

Leptospirosis is been considered an important infectious disease that affects humans and
animals worldwide. This review summarizes our current knowledge of bacterial attachment …

Microbial surface and secreted proteins (the secretome) contain a large number of proteins
that interact with other microbes, host and/or environment. These proteins are exported by …

The virulence mechanisms required for infection and evasion of immunity by pathogenic
Leptospira species remain poorly understood. A number of L. interrogans surface proteins …

Zoonotic diseases are infectious diseases that pass from animals to humans. These include
diseases caused by viruses, bacteria, fungi, and parasites and can be transmitted through …

Leptospirosis, caused by pathogenic species of Leptospira, is the most widespread
zoonosis and has emerged as a major public health problem worldwide. The adhesion of …

The complement system consists of more than 40 proteins that participate in the
inflammatory response and in pathogen killing. Complement inhibitors are necessary to …

Pathogenic spirochetes of the genus Leptospira are the causative agents of leptospirosis, a
zoonotic infection that occurs globally. The bacteria colonize the renal proximal tubules of …