Nucleic acid amplification has permeated every field in the life sciences since the
introduction of the classic polymerase chain reaction (PCR) method in 1983. Yet, despite its …

Recombinase polymerase amplification (RPA) is a highly sensitive and selective isothermal
amplification technique, operating at 37–42° C, with minimal sample preparation and …

Detection of pathogens, eg, bacteria and viruses, is still a big challenge in analytical
medicine due to their vast number and variety. Developing strategies for rapid, inexpensive …

Bacterial infections remain one of the principal causes of morbidity and mortality worldwide.
The number of deaths due to infections is declining every year by only 1% with a forecast of …

Background Update diagnostic methods play essential roles in dealing with the current
global malaria situation and decreasing malaria incidence. Aim Global malaria control …

The easy and rapid spread of bacterial contamination and the risk it poses to human health
makes evident the need for analytical methods alternative to conventional time-consuming …

Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and
express genetic information, which play central roles in diverse cellular events and diseases …

Multiplexed isothermal amplification and detection of nucleic acid sequences and
biomarkers is of increasing importance in diverse areas including advanced diagnostics …

Abstract Salmonella Typhimurium (S. Typhimurium) can cause serious foodborne diseases.
In this study, an assay combining recombinase polymerase amplification (RPA) with lateral …

Shigella spp. and enteroinvasive Escherichia coli (EIEC) are widely distributed and can
cause serious food-borne diseases for humans such as dysentery. Therefore, an efficient …