Block co-polymeric micelles receive increased attention due to their ability to load therapeutics, deliver the cargo to the site of action, improve the pharmacokinetic of the …
The rapid recognition of intravenously injected colloidal carriers, such as liposomes and polymeric nanospheres from the blood by Kupffer cells, has initiated a surge of development …
Micelles, self-assembling nanosized colloidal particles with a hydrophobic core and hydrophilic shell are currently successfully used as pharmaceutical carriers for water …
VP Torchilin - Journal of controlled release, 2001 - Elsevier
The review concentrates on the use of polymeric micelles as pharmaceutical carriers. Micellization of biologically active substances is a general phenomenon that increases the …
K Letchford, H Burt - European journal of pharmaceutics and …, 2007 - Elsevier
Amphiphilic block copolymers are able to form a range of different nanoparticulate structures. These include micelles, nanospheres, nanocapsules, and polymersomes. This …
MC Jones, JC Leroux - European journal of pharmaceutics and …, 1999 - Elsevier
Polymeric micelles have recently emerged as a novel promising colloidal carrier for the targeting of poorly water soluble and amphiphilic drugs. Polymeric micelles are considerably …
Amphiphilic block copolymers (ABCs) have been used extensively in pharmaceutical applications ranging from sustained-release technologies to gene delivery. The utility of …
C Allen, D Maysinger, A Eisenberg - Colloids and Surfaces B: Biointerfaces, 1999 - Elsevier
This review describes the properties of block copolymer micelles which influence their efficiency as drug delivery vehicles for hydrophobic drugs. The key performance related …
SR Croy, GS Kwon - Current pharmaceutical design, 2006 - ingentaconnect.com
Polymeric micelles are nanoscopic core/shell structures formed by amphiphilic block copolymers. Both the inherent and modifiable properties of polymeric micelles make them …