T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Adaptive response of T and B cells in atherosclerosis

DFJ Ketelhuth, GK Hansson - Circulation research, 2016 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and
accumulation of cholesterol-containing lipoproteins, particularly low-density lipoprotein, in …

Inflammation and atherosclerosis

GK Hansson, AKL Robertson… - Annu. Rev. Pathol …, 2006 - annualreviews.org
Atherosclerosis, the cause of myocardial infarction, stroke, and ischemic gangrene, is an
inflammatory disease. The atherosclerotic process is initiated when cholesterol-containing …

The IL-33/ST2 pathway: therapeutic target and novel biomarker

R Kakkar, RT Lee - Nature reviews Drug discovery, 2008 - nature.com
For many years, the interleukin-1 receptor family member ST2 was an orphan receptor that
was studied in the context of inflammatory and autoimmune disease. However, in 2005, a …

Immunobiology of atherosclerosis: a complex net of interactions

B Herrero-Fernandez, R Gomez-Bris… - International Journal of …, 2019 - mdpi.com
Cardiovascular disease is the leading cause of mortality worldwide, and atherosclerosis the
principal factor underlying cardiovascular events. Atherosclerosis is a chronic inflammatory …

PET/MR imaging of inflammation in atherosclerosis

ML Senders, C Calcagno, A Tawakol… - Nature Biomedical …, 2023 - nature.com
Myocardial infarction, stroke, mental disorders, neurodegenerative processes, autoimmune
diseases, cancer and the human immunodeficiency virus impact the haematopoietic system …

Adaptive immunity and atherosclerosis

J Andersson, P Libby, GK Hansson - Clinical immunology, 2010 - Elsevier
Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most
common causes of death globally. It has been evident for more than 20 years that adaptive …

Adaptive (T and B cells) immunity and control by dendritic cells in atherosclerosis

H Ait-Oufella, AP Sage, Z Mallat, A Tedgui - Circulation research, 2014 - Am Heart Assoc
Chronic inflammation in response to lipoprotein accumulation in the arterial wall is central in
the development of atherosclerosis. Both innate and adaptive immunity are involved in this …

T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice

V Bazioti, AM La Rose, S Maassen, F Bianchi… - Nature …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease driven by hypercholesterolemia. During
aging, T cells accumulate cholesterol, potentially affecting inflammation. However, the effect …