[HTML][HTML] Individual cell types in C. elegans age differently and activate distinct cell-protective responses

AE Roux, H Yuan, K Podshivalova, D Hendrickson… - Cell Reports, 2023 - cell.com
Aging is characterized by a global decline in physiological function. However, by
constructing a complete single-cell gene expression atlas, we find that Caenorhabditis …

Forkhead transcription factor FKH-8 cooperates with RFX in the direct regulation of sensory cilia in Caenorhabditis elegans

R Brocal-Ruiz, A Esteve-Serrano, C Mora-Martínez… - Elife, 2023 - elifesciences.org
Cilia, either motile or non-motile (aka primary or sensory), are complex evolutionarily
conserved eukaryotic structures composed of hundreds of proteins required for their …

The complete cell atlas of an aging multicellular organism

AE Roux, H Yuan, K Podshivalova, D Hendrickson… - Biorxiv, 2022 - biorxiv.org
Here we describe a single-cell atlas of aging for the nematode Caenorhabditis elegans. This
unique resource describes the expression across adulthood of over 20,000 genes among …

Physiological insight into the conserved properties of Caenorhabditis elegans acid‐sensing degenerin/epithelial sodium channels

E Kaulich, PTN McCubbin, WR Schafer… - The Journal of …, 2023 - Wiley Online Library
Acid‐sensing ion channels (ASICs) are members of the diverse family of
degenerin/epithelial sodium channels (DEG/ENaCs). They perform a wide range of …

The C. elegans regulatory factor X (RFX) DAF-19M module: A shift from general ciliogenesis to cell-specific ciliary and behavioral specialization

S Ahn, H Yang, S Son, HS Lee, D Park, H Yim, HJ Choi… - Cell Reports, 2022 - cell.com
Cilia are important for the interaction with environments and the proper function of tissues.
While the basic structure of cilia is well conserved, ciliated cells have various functions. To …

DAF‐19/RFX controls ciliogenesis and influences oxygen‐induced social behaviors in Pristionchus pacificus

E Moreno, M Lenuzzi, C Rödelsperger… - Evolution & …, 2018 - Wiley Online Library
Cilia are complex organelles involved in sensory perception and motility with intraflagellar
transport (IFT) proteins being essential for cilia assembly and function, but little is known …

Vibration sensitivity found in Caenorhabditis elegans

RI Holbrook, B Mortimer - Journal of Experimental Biology, 2018 - journals.biologists.com
Mechanical sensing is important for all organisms, but is the least understood of the senses.
As mechanical stimuli come in diverse forms, organisms often have sensors or sensory …

Primary cilia promote the differentiation of human neurons through the WNT signaling pathway

A Coschiera, M Yoshihara, G Lauter, S Ezer, M Pucci… - BMC biology, 2024 - Springer
Background Primary cilia emanate from most human cell types, including neurons. Cilia are
important for communicating with the cell's immediate environment: signal reception and …

The C. elegans DAF-19M module: a shift from general ciliogenesis to ciliary and behavioral specialization

S Ahn, H Yang, S Son, D Park, H Yim, P Swoboda… - BioRxiv, 2021 - biorxiv.org
In animals, cilia are important for the interaction with environments and the proper function of
tissues and organs. Understanding the distinctive identities of each type of ciliated cell is …

Transcriptional regulatory logic of cilium formation in c. Elegans

R Brocal Ruiz - 2022 - riunet.upv.es
[ES] Los cilios son estructuras eucariotas complejas conservadas evolutivamente que,
proyectando desde la superficie de las células, desempeñan un gran número de funciones …