Aim Diabetes is increasing in prevalence worldwide, with a 20% rise in prevalence
predicted between 2021 and 2030, bringing an increased burden of complications, such as …

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD), and
its pathogenesis has not been clarified. Current research suggests that DKD involves …

Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease. As many
genes associate with DKD, multi-omics approaches were employed to narrow the list of …

ABSTRACT Matrix metalloproteinase 7 (MMP-7) is a secreted endopeptidase involved in the
degradation of extracellular matrix components and the activation of cytokines and growth …

Background: In autosomal dominant polycystic kidney disease (ADPKD) there is an unmet
need for early markers of rapid disease progression to facilitate counseling and selection for …

Background Clinical observations have recently shown that Abelmoschus manihot (L.) in the
form of Huangkui capsule (HKC) and in combination with irbesartan (EB) is an effective …

Diabetic kidney disease (DKD) is characterized by complex pathogenesis and poor
prognosis; therefore, an exploration of novel etiological factors may be beneficial. Despite …

There has been limited research on assessing metalloproteinases (MMPs) 1, 2, and 7, as
well as their tissue inhibitors (TIMPs) 1, 2, 3, and 4 in the context of polytrauma. These …

Diabetic kidney disease (DKD) is a prevalent microvascular complication of diabetes
mellitus and a primary cause of end-stage renal disease (ESRD). Increasing studies suggest …

Background Kidney fibrosis is the common final pathway of virtually all advanced forms of
chronic kidney disease (CKD) including diabetic nephropathy (DN), IgA nephropathy (IgAN) …