The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …

Hypericum perforatum (Hypericaceae), known as Saint John's wort (SJW), has been used in
different systems of traditional medicine such as Chinese traditional medicine, Greek …

Hypericin can be derived from St. John's wort, which is widely spread around the world. As a
natural product, it has been put into clinical practice such as wound healing and depression …

Diabetes mellitus is a very common chronic disease with progressively increasing
prevalence. Besides the well-known autoimmune and inflammatory pathogenesis of type 1 …

Medicinal herb infusions can be used for the treatment of obesity-related metabolic
alterations. The aim of this study was to characterize the phytochemical profile and to …

Herbal medicines are frequently used for the prevention and treatment of obesity and
obesity-related disorders. Our preliminary screening showed that St. John's Wort (SJW) …

Ethnopharmacological relevance Hypericum perforatum L., commonly known as St. John's
Wort (SJW), represents one of the best-known and most thoroughly researched medicinal …

Any defects in bile formation, secretion, or flow may give rise to cholestasis, liver fibrosis,
cirrhosis, and hepatocellular carcinoma. As the pathogenesis of hepatic disorders is …

The incidence of cardiometabolic disease is increasing globally, with a trend toward
younger age of onset. Among these, atherosclerotic cardiovascular disease is a leading …

Obesity affects more than 10% of the adult population globally. Despite the introduction of
diverse medications aimed at combating fat accumulation and obesity, a significant number …