Weight gain after HIV therapy initiation: pathophysiology and implications

NC Chandiwana, MJ Siedner… - The Journal of …, 2024 - academic.oup.com
Rapid advances in the potency, safety, and availability of modern HIV antiretroviral therapy
(ART) have yielded a near-normal life expectancy for most people living with HIV (PLWH) …

HIV-1 transcriptional modulation: Novel host factors and prospective therapeutic strategies

QMR Gibaut, LP Mori, ST Valente - Current Opinion in HIV and …, 2023 - journals.lww.com
The HIV-1 latent reservoir is established early after infection, persists during antiretroviral
therapy, and is the source of viral rebound after treatment interruption. An HIV cure requires …

Major revision version 12.0 of the European AIDS Clinical Society guidelines 2023

J Ambrosioni, L Levi, J Alagaratnam… - HIV …, 2023 - Wiley Online Library
Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised
in 2023 for the 19th time, and all aspects of HIV care were updated. Key Points of the …

Time Trends in Causes of Death in People With Human Immunodeficiency Virus: Insights From the Swiss HIV Cohort Study

MSR Weber, JJ Duran Ramirez… - Clinical infectious …, 2024 - academic.oup.com
Background Advancements in access to antiretroviral therapy (ART) and human
immunodeficiency virus (HIV) care have led to a decline in AIDS-related deaths among …

Trends in Mortality in People With HIV From 1999 through 2020: A Multicohort Collaboration

E Tusch, L Ryom, A Pelchen-Matthews… - Clinical Infectious …, 2024 - academic.oup.com
Background Mortality among people with human immunodeficiency virus (HIV) declined with
the introduction of combination antiretroviral therapy. We investigated trends in mortality in …

Weight, anthropometric and metabolic changes after discontinuing antiretroviral therapy containing tenofovir alafenamide in people with HIV

J Damas, A Munting, J Fellay, D Haerry… - Clinical Infectious …, 2024 - academic.oup.com
Background Antiretroviral therapy (ART)-related weight gain is of particular concern in
people with HIV (PWH). Although weight gain was observed among PWH receiving tenofovir …

Expanding HIV clinical monitoring: the role of CD4, CD8, and CD4/CD8 ratio in predicting non-AIDS events

J Martínez-Sanz, J Díaz-Álvarez, MR Cancio-Suarez… - …, 2023 - thelancet.com
Background While a low CD4/CD8 ratio during HIV treatment correlates with
immunosenescence, its value in identifying patients at an increased risk for clinical events …

Examining Chronic Inflammation, Immune Metabolism, and T Cell Dysfunction in HIV Infection

W Mu, V Patankar, S Kitchen, A Zhen - Viruses, 2024 - mdpi.com
Chronic Human Immunodeficiency Virus (HIV) infection remains a significant challenge to
global public health. Despite advances in antiretroviral therapy (ART), which has …

Blood-based protein biomarkers during the acute ischemic stroke treatment window: a systematic review

J Rahmig, A Chanpura, A Schultz, FC Barone… - Frontiers in …, 2024 - frontiersin.org
Background Rapid and accurate acute ischemic stroke (AIS) diagnosis is needed to
expedite emergent thrombolytic and mechanical thrombectomy treatment. Changes in blood …

Hospitalizations and deaths among people coinfected with HIV and HCV

D Zarębska-Michaluk, P Rzymski, K Kanecki… - Scientific Reports, 2024 - nature.com
Coinfection with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) remains a
significant public health challenge. This retrospective, population-based study assessed the …