Nutrition in early life and the programming of adult disease: a review

SC Langley‐Evans - Journal of Human Nutrition and Dietetics, 2015 - Wiley Online Library
Foetal development and infancy are life stages that are characterised by rapid growth,
development and maturation of organs and systems. Variation in the quality or quantity of …

[HTML][HTML] Intrauterine growth restriction: Clinical consequences on health and disease at adulthood

JB Armengaud, C Yzydorczyk, B Siddeek… - Reproductive …, 2021 - Elsevier
Intrauterine growth restriction (IUGR) affects 10–15% of all pregnancies worldwide. IUGR
may result from maternal, placental or fetal origin. Maternal malnutrition before and during …

DNA methylation in nonalcoholic fatty liver disease

J Hyun, Y Jung - International journal of molecular sciences, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a widespread hepatic disorder in the United
States and other Westernized countries. Nonalcoholic steatohepatitis (NASH), an advanced …

Developmental origins of adult disease

SC Langley-Evans, S McMullen - Medical principles and practice, 2010 - karger.com
Variation in the quality or quantity of nutrients consumed during pregnancy can exert
permanent and powerful effects upon the developing fetus. This programming of fetal …

Fetal programming: link between early nutrition, DNA methylation, and complex diseases

A Chmurzynska - Nutrition reviews, 2010 - academic.oup.com
Complex traits, including those involved in diet-related diseases, are determined by multiple
genes and environmental influences. Factors influencing the development of complex traits …

Nutritional programming of disease: unravelling the mechanism

SC Langley‐Evans - Journal of anatomy, 2009 - Wiley Online Library
Nutritional programming is the process through which variation in the quality or quantity of
nutrients consumed during pregnancy exerts permanent effects upon the developing fetus …

The relationship between maternal depressive, anxious, and stress symptoms during pregnancy and adult offspring behavioral and emotional problems

KS Betts, GM Williams, JM Najman… - Depression and …, 2015 - Wiley Online Library
Background Prenatal maternal depressive, anxious, and stress symptoms have been found
to be associated with child and adolescent behavior problems. In this paper, we investigate …

[HTML][HTML] Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition

GC Burdge, KA Lillycrop, ES Phillips… - The Journal of …, 2009 - Elsevier
Prenatal nutritional constraint is associated with increased risk of metabolic dysregulation in
adulthood contingent on adult diet. In rats, folic acid supplementation of a protein-restricted …

Low and high birth weights are risk factors for nonalcoholic fatty liver disease in children

KP Newton, HS Feldman, CD Chambers, L Wilson… - The Journal of …, 2017 - Elsevier
Objectives To examine the distribution of birth weight in children with nonalcoholic fatty liver
disease (NAFLD) compared with the general US population, and to investigate the …

Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes

D Ferland-McCollough, DS Fernandez-Twinn… - Cell Death & …, 2012 - nature.com
Nutrition during early mammalian development permanently influences health of the adult,
including increasing the risk of type 2 diabetes and coronary heart disease. However, the …