MYC oncogene is a transcription factor with a wide array of functions affecting cellular
activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to …

MicroRNAs (miRNAs) are short non-coding RNAs with a length of∼ 22 nucleotides,
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …

MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and
stability of messenger RNAs (mRNAs), controlling genes involved in cellular processes such …

With the advent of next generation sequencing techniques a previously unknown world of
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Since the identification of microRNAs (miRNAs) in 1993, and the subsequent discovery of
their highly conserved nature in 2000, the amount of research into their function …

While the tumor suppressor functions of p53 have long been recognized, the contribution of
p53 to numerous other aspects of disease and normal life is only now being appreciated …

A biomarker with high specificity and sensitivity, is a basic requirement for non‐invasive
cancer diagnosis. Exosomes are a type of lipid bilayer extracellular vesicles (EVs) …

Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the
scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent …

Recently, the transcription factor encoded by tumor suppressor gene p53 was shown to
regulate the expression of microRNAs. The most significant induction by p53 was observed …