Bacterial microcompartments

CA Kerfeld, C Aussignargues, J Zarzycki… - Nature Reviews …, 2018 - nature.com
Bacterial microcompartments (BMCs) are self-assembling organelles that consist of an
enzymatic core that is encapsulated by a selectively permeable protein shell. The potential …

Protein-based organelles in bacteria: carboxysomes and related microcompartments

TO Yeates, CA Kerfeld, S Heinhorst… - Nature Reviews …, 2008 - nature.com
Many bacteria contain intracellular microcompartments with outer shells that are composed
of thousands of protein subunits and interiors that are filled with functionally related …

A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia

SI Lee, S Celik, BA Logsdon, SM Lundberg… - Nature …, 2018 - nature.com
Cancers that appear pathologically similar often respond differently to the same drug
regimens. Methods to better match patients to drugs are in high demand. We demonstrate a …

[HTML][HTML] Biogenesis of a bacterial organelle: the carboxysome assembly pathway

JC Cameron, SC Wilson, SL Bernstein, CA Kerfeld - Cell, 2013 - cell.com
The carboxysome is a protein-based organelle for carbon fixation in cyanobacteria,
keystone organisms in the global carbon cycle. It is composed of thousands of subunits …

Structural basis of enzyme encapsulation into a bacterial nanocompartment

M Sutter, D Boehringer, S Gutmann… - Nature structural & …, 2008 - nature.com
Compartmentalization is an important organizational feature of life. It occurs at varying levels
of complexity ranging from eukaryotic organelles and the bacterial microcompartments, to …

Subcellular organization: a critical feature of bacterial cell replication

IV Surovtsev, C Jacobs-Wagner - Cell, 2018 - cell.com
Spatial organization is a hallmark of all living systems. Even bacteria, the smallest forms of
cellular life, display defined shapes and complex internal organization, showcasing a highly …

Lambda Red-mediated recombinogenic engineering of enterohemorrhagic and enteropathogenic E. coli

KC Murphy, KG Campellone - BMC molecular biology, 2003 - Springer
Abstract Background The λ Red recombineering technology has been used extensively in
Escherichia coli and Salmonella typhimurium for easy PCR-mediated generation of deletion …

Bacterial microcompartments

CA Kerfeld, S Heinhorst… - Annual review of …, 2010 - annualreviews.org
Bacterial microcompartments (BMCs) are organelles composed entirely of protein. They
promote specific metabolic processes by encapsulating and colocalizing enzymes with their …

Diverse bacterial microcompartment organelles

C Chowdhury, S Sinha, S Chun… - Microbiology and …, 2014 - Am Soc Microbiol
Bacterial microcompartments (MCPs) are sophisticated protein-based organelles used to
optimize metabolic pathways. They consist of metabolic enzymes encapsulated within a …

Solution structure of a bacterial microcompartment targeting peptide and its application in the construction of an ethanol bioreactor

AD Lawrence, S Frank, S Newnham, MJ Lee… - ACS synthetic …, 2014 - ACS Publications
Targeting of proteins to bacterial microcompartments (BMCs) is mediated by an 18-amino-
acid peptide sequence. Herein, we report the solution structure of the N-terminal targeting …