Inflammation is a key driver in many pathological conditions such as allergy, cancer,
Alzheimer's disease, and many others, and the current state of available drugs prompted …

Macrophages are the most abundant immune cells within the synovial joints, and also the
main innate immune effector cells triggering the initial inflammatory responses in the …

Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …

Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …

Inflammation is the most common feature of many chronic diseases and complications, while
playing critical roles in carcinogenesis. Several studies have demonstrated that Nrf2 …

Large-scale breeding environments often lead to oxidative stress. Macrophages play an
important role in the immune system and are vulnerable to reactive oxygen species (ROS) …

Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …

Andrographolide is a labdane diterpene and the main active ingredient isolated from the
herb Andrographis paniculata. Andrographolide possesses diverse biological effects …

Curcumin is a naturally occurring polyphenol that is isolated from the rhizome of Curcuma
longa (turmeric). This medicinal compound has different biological activities, including …

Research into human biotransformation and elimination systems continues to evolve.
Various clinical and in vivo studies have been undertaken to evaluate the effects of foods …