Over the years, much research has been focused on the use of small molecules such as
peptides or aptamers or more recently on the use of variable antigen-binding domain of …

The exposure of cancer cells to subtherapeutic drug concentrations results in multidrug
resistance (MDR). The uniqueness of mesoporous silica nanoparticles (MSNPs) with larger …

The immediate release of chemotherapeutics at the target site, along with no premature
release in circulation is always challenging. The purpose of this study was to develop a …

In this study, the potential cytotoxicity of four plant extracts originated from Cameroon:
Xylopia aethiopica (XA), Imperata cylindrica (IC), Echinops giganteus (EG) and Dorstenia …

Purpose Lipoparticles are the core-shell type lipid-polymer hybrid systems comprising
polymeric nanoparticle core enveloped by single or multiple pegylated lipid layers (shell) …

Hypoxia, an oxygen-deprived condition of the tumor, is one of the major reasons for
resistance to chemotherapy. Carbonic anhydrases are generally involved in pH …

An aptamer is a sequence of DNA or RNA that binds to a certain target with a high
specificity. Aptamer-functionalized nanocarriers are privileged with several advantages that …

Over a century ago, Paul Ehrlich's theory about specific binding of antigens to receptors in
immunology is now also applied to the binding of drugs towards various types of cell …