[HTML][HTML] Circular RNAs in cancer
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …
Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
The bioinformatics toolbox for circRNA discovery and analysis
Circular RNAs (circRNAs) are a unique class of RNA molecule identified more than 40 years
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
A 360 view of circular RNAs: From biogenesis to functions
JE Wilusz - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
The first circular RNA (circRNA) was identified more than 40 years ago, but it was only
recently appreciated that circRNAs are common outputs of many eukaryotic protein‐coding …
recently appreciated that circRNAs are common outputs of many eukaryotic protein‐coding …
A comprehensive overview and evaluation of circular RNA detection tools
Circular RNA (circRNA) is mainly generated by the splice donor of a downstream exon
joining to an upstream splice acceptor, a phenomenon known as backsplicing. It has been …
joining to an upstream splice acceptor, a phenomenon known as backsplicing. It has been …
A circular RNA promotes tumorigenesis by inducing c-myc nuclear translocation
Circular RNAs (circRNAs) are a subclass of noncoding RNAs widely expressed in
mammalian cells. We report here the tumorigenic capacity of a circRNA derived from …
mammalian cells. We report here the tumorigenic capacity of a circRNA derived from …
Circular RNA: an emerging key player in RNA world
Insights into the circular RNA (circRNA) exploration have revealed that they are abundant in
eukaryotic transcriptomes. Diverse genomic regions can generate different types of RNA …
eukaryotic transcriptomes. Diverse genomic regions can generate different types of RNA …
Lessons from non-canonical splicing
Recent improvements in experimental and computational techniques that are used to study
the transcriptome have enabled an unprecedented view of RNA processing, revealing many …
the transcriptome have enabled an unprecedented view of RNA processing, revealing many …
Circular RNAs: a novel class of functional RNA molecules with a therapeutic perspective
Circular RNAs (circRNAs) are a subclass of non-coding RNAs that lack free 3′ and 5′
ends and, thus, exist as continuous loop RNAs. Such circular transcripts have been …
ends and, thus, exist as continuous loop RNAs. Such circular transcripts have been …
[HTML][HTML] CircACC1 regulates assembly and activation of AMPK complex under metabolic stress
Q Li, Y Wang, S Wu, Z Zhou, X Ding, R Shi, RF Thorne… - Cell metabolism, 2019 - cell.com
We report that circACC1, a circular RNA derived from human ACC1, plays a critical role in
cellular responses to metabolic stress. CircACC1 is preferentially produced over ACC1 in …
cellular responses to metabolic stress. CircACC1 is preferentially produced over ACC1 in …