Epigenetic alterations in the gastrointestinal tract: current and emerging use for biomarkers of cancer

WM Grady - Advances in cancer research, 2021 - Elsevier
Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …

The impact of biomarkers in pancreatic ductal adenocarcinoma on diagnosis, surveillance and therapy

N Sturm, TJ Ettrich, L Perkhofer - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma is a leading cause of cancer death
worldwide. Due to the frequently late diagnosis, early metastasis and high therapy …

Epigenetic alterations in pancreatic cancer metastasis

SS Wang, J Xu, KY Ji, CI Hwang - Biomolecules, 2021 - mdpi.com
Pancreatic cancer is the third leading cause of cancer-related deaths in the United States.
Pancreatic ductal adenocarcinoma (PDA) is the most common (90%) and aggressive type of …

Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA

H Wu, S Guo, X Liu, Y Li, Z Su, Q He, X Liu, Z Zhang… - BMC medicine, 2022 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) has the lowest overall survival rate
primarily due to the late onset of symptoms and rapid progression. Reliable and accurate …

[HTML][HTML] Early diagnosis of pancreatic cancer: What strategies to avoid a foretold catastrophe

V Tonini, M Zanni - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
While great strides in improving survival rates have been made for most cancers in recent
years, pancreatic ductal adenocarcinoma (PDAC) remains one of the solid tumors with the …

Prognostic value of circulating tumour DNA in metastatic pancreatic cancer patients: post-hoc analyses of two clinical trials

D Pietrasz, S Wang-Renault, J Taieb, L Dahan… - British Journal of …, 2022 - nature.com
Objective The prognostication of metastatic pancreatic adenocarcinoma (mPDAC) patients
remains uncertain, mainly based on carbohydrate antigen 19-9 (CA19-9), with limited utility …

Circulating tumor DNA methylation biomarkers for characterization and determination of the cancer origin in malignant liver tumors

T Draškovič, N Zidar, N Hauptman - Cancers, 2023 - mdpi.com
Simple Summary Malignant liver tumors consist of primary tumors and metastases. A correct
diagnosis can be achieved with different methods; one of them is the analysis of the cell-free …

Diagnostic, predictive and prognostic molecular biomarkers in pancreatic cancer: An overview for clinicians

D Giannis, D Moris, AS Barbas - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic cancer is the fourth most common cancer-related cause of
death in the United States and is usually asymptomatic in early stages. There is a scarcity of …

Clinical implementation and current advancement of blood liquid biopsy in cancer

K Watanabe, Y Nakamura, SK Low - Journal of Human Genetics, 2021 - nature.com
Liquid biopsies have been receiving tremendous attentions as easy, rapid, and non-invasive
tools for cancer diagnosis. Liquid biopsy can be performed repeatedly for disease …

[HTML][HTML] Emerging role of non-invasive and liquid biopsy biomarkers in pancreatic cancer

A Bararia, P Chakraborty, P Roy… - World Journal of …, 2023 - ncbi.nlm.nih.gov
A global increase in the incidence of pancreatic cancer (PanCa) presents a major concern
and health burden. The traditional tissue-based diagnostic techniques provided a major way …