Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers
TJ Kinsella - Clinical Cancer Research, 2009 - AACR
DNA damage processing by mismatch repair (MMR) and/or base excision repair (BER) can
determine the therapeutic index following treatment of human cancers using radiation …
determine the therapeutic index following treatment of human cancers using radiation …
A rapid, simple DNA mismatch repair substrate construction method
W Du, TJ Kinsella - Frontiers in Oncology, 2011 - frontiersin.org
A more flexible and higher-yielding in vitro DNA mismatch repair (MMR) substrate
construction method, which was developed initially by Wang and Hays, is described for the …
construction method, which was developed initially by Wang and Hays, is described for the …
Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA …
TJ Kinsella, E Gurkan-Cavusoglu, W Du… - Frontiers in …, 2011 - frontiersin.org
Over the last 7 years, we have focused our experimental and computational research efforts
on improving our understanding of the biochemical, molecular, and cellular processing of …
on improving our understanding of the biochemical, molecular, and cellular processing of …
Quantitative analysis of the effects of iododeoxyuridine and ionising radiation treatment on the cell cycle dynamics of DNA mismatch repair deficient human colorectal …
E Gurkan‐Cavusoglu, JE Schupp… - IET systems …, 2013 - Wiley Online Library
DNA mismatch repair (MMR) is involved in processing DNA damage following treatment
with ionising radiation (IR) and various classes of chemotherapy drugs including …
with ionising radiation (IR) and various classes of chemotherapy drugs including …