Plasminogen activators, tissue degradation, and cancer

K Danø, PA Andreasen, J Grøndahl-Hansen… - Advances in cancer …, 1985 - Elsevier
Publisher Summary This chapter discusses the role of plasminogen activators in various
biological processes. In specific, it describes two types of plasminogen activators—namely …

Plasminogen activation and regulation of pericellular proteolysis

O Saksela - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1985 - Elsevier
II. Plasminogen activation...................................................................... A. Mechanism of
plasminogen activation......................................................... B. Plasminogen …

[HTML][HTML] Purification and characterization of the plasminogen activator secreted by human melanoma cells in culture.

DC Rijken, D Collen - Journal of Biological Chemistry, 1981 - Elsevier
The plasminogen activator secreted by a cultured human melanoma cell line was purified
and compared with urokinase and with tissue plasminogen activator from human uterus. The …

Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells.

DJ Loskutoff, JA Van Mourik… - Proceedings of the …, 1983 - National Acad Sciences
Fibrin/agar films were prepared and used to detect plasminogen activators produced by
cultured bovine aortic endothelial cells (fibrin autography). One preparation of fibrin …

Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells.

EG Levin, U Marzec, J Anderson… - The Journal of clinical …, 1984 - Am Soc Clin Investig
The effect of thrombin on the release of tissue plasminogen activator from endothelial cells
was studied in primary cultures of human umbilical vein endothelial cells. Tissue …

The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type.

EF Plow, DE Freaney, J Plescia, LA Miles - The Journal of cell biology, 1986 - rupress.org
The capacity of cells to interact with the plasminogen activator, urokinase, and the zymogen,
plasminogen, was assessed using the promyeloid leukemic U937 cell line and the diploid …

Cultured bovine endothelial cells produce both urokinase and tissue-type plasminogen activators.

EG Levin, DJ Loskutoff - The Journal of cell biology, 1982 - rupress.org
Cell extracts and conditioned media (CM) from cultured bovine aortic endothelial cells
(BAEs) were fractionated by PAGE in the presence SDS, and plasminogen activator (PA) …

Urokinase-and tissue-type plasminogen activators in keratinocytes during wound reepithelialization in vivo

J Grøndahl-Hansen, LR Lund, E Ralfkiær… - Journal of investigative …, 1988 - Elsevier
Urokinase-and tissue-type plasminogen activators (u-PA and t-PA) were identified
immunohistochemically during re-epithelialization of mouse and human skin wounds, by …

Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line

K Miyazaki, Y Hattori, F Umenishi, H Yasumitsu… - Cancer Research, 1990 - AACR
A metalloproteinase with M r 29,000 was purified to homogeneity as a latent proenzyme
from the conditioned medium of a human rectal carcinoma cell line CaR-1. This enzyme …

St John's Wort (Hypericum perforatum L.) Photomedicine: Hypericin-Photodynamic Therapy Induces Metastatic Melanoma Cell Death

B Kleemann, B Loos, TJ Scriba, D Lang, LM Davids - PloS one, 2014 - journals.plos.org
Hypericin, an extract from St John's Wort (Hypericum perforatum L.), is a promising
photosensitizer in the context of clinical photodynamic therapy due to its excellent …