Sarcopenia in cirrhosis: from pathogenesis to interventions

M Ebadi, RA Bhanji, VC Mazurak… - Journal of …, 2019 - Springer
Sarcopenia (severe muscle depletion) is a prevalent muscle abnormality in patients with
cirrhosis that confers poor prognosis both pre-and post-liver transplantation. The …

[HTML][HTML] Forcing the vicious circle: sarcopenia increases toxicity, decreases response to chemotherapy and worsens with chemotherapy

F Bozzetti - Annals of oncology, 2017 - Elsevier
Sarcopenia has recently emerged as a new condition that, independently from malnutrition,
may adversely affect the prognosis of cancer patients. Purpose of this narrative review is to …

Exercise training during chemotherapy preserves skeletal muscle fiber area, capillarization, and mitochondrial content in patients with breast cancer

S Mijwel, DA Cardinale, J Norrbom… - The FASEB …, 2018 - Wiley Online Library
Exercise has been suggested to ameliorate the detrimental effects of chemotherapy on
skeletal muscle. The aim of this study was to compare the effects of different exercise …

CD44 mediated colon cancer targeting mutlifaceted lignin nanoparticles: Synthesis, in vitro characterization and in vivo efficacy studies

L Siddiqui, N Hasan, PK Mishra, N Gupta… - International Journal of …, 2023 - Elsevier
Hyaluronic acid (HA) coated irinotecan loaded lignin nanoparticles (HDLNPs) were
synthesized using ionic interaction method. Optimized nanoparticles were characterized for …

Fiber typing human skeletal muscle with fluorescent immunohistochemistry

KA Murach, CM Dungan, K Kosmac… - Journal of Applied …, 2019 - journals.physiology.org
Skeletal muscle myosin heavy chain (MyHC) fiber type composition is a critical determinant
of overall muscle function and health. Various approaches interrogate fiber type at the single …

[HTML][HTML] Mitochondrial dynamics in cancer-induced cachexia

M van der Ende, S Grefte, R Plas, J Meijerink… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Cancer-induced cachexia has a negative impact on quality of life and adversely affects
therapeutic outcomes and survival rates. It is characterized by, often severe, loss of muscle …

Skeletal muscle function during the progression of cancer cachexia in the male ApcMin/+ mouse

BN VanderVeen, JP Hardee, DK Fix… - Journal of applied …, 2018 - journals.physiology.org
While cancer-induced skeletal muscle wasting has been widely investigated, the drivers of
cancer-induced muscle functional decrements are only beginning to be understood …

Exploring heterogeneity: A dive into preclinical models of cancer cachexia

F Morena, AR Cabrera… - American Journal of …, 2024 - journals.physiology.org
Cancer cachexia (CC) is a multifactorial and complex syndrome experienced by up to 80%
of patients with cancer and implicated in∼ 40% of cancer-related deaths. Given its …

[HTML][HTML] The aging athlete: paradigm of healthy aging

KJ Gries, SW Trappe - International journal of sports medicine, 2022 - thieme-connect.com
The Exercise Boom of the 1970's resulted in the adoption of habitual exercise in a significant
portion of the population. Many of these individuals are defying the cultural norms by …

[HTML][HTML] Aspirin alleviates denervation-induced muscle atrophy via regulating the Sirt1/PGC-1α axis and STAT3 signaling

Q Wan, L Zhang, Z Huang, H Zhang, J Gu… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Our prior studies have shown that inflammation may play an important
triggering role during the process of denervated muscle atrophy. The nonsteroidal anti …