The chemistry of poly (2-oxazoline) s

B Verbraeken, BD Monnery, K Lava… - European Polymer …, 2017 - Elsevier
As we celebrate the 50th birthday of the discovery of poly (2-alkyl/aryl-2-oxazoline) s (PAOx)
this year we see a research field that is rapidly expanding after some lesser academic …

Poly (2‐oxazoline) s: A comprehensive overview of polymer structures and their physical properties

M Glassner, M Vergaelen… - Polymer …, 2018 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (PAOx) are of increasing importance for a wide range of
applications, mostly in the biomedical field. This review describes the synthesis of 2 …

Drug Delivery Systems Based on Poly (2‐oxazoline) s and Poly (2‐oxazine) s

O Sedlacek, R Hoogenboom - Advanced Therapeutics, 2020 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (PAOx) represent an established class of polymer materials
with a wide range of applications. In contrast, the homologous poly (2‐oxazine) s (PAOzi) …

Amidation of methyl ester-functionalised poly (2-oxazoline) s as a powerful tool to create dual pH-and temperature-responsive polymers as potential drug delivery …

MN Leiske, R Singha, S Jana, BG De Geest… - Polymer …, 2023 - pubs.rsc.org
In the past two decades, thermoresponsive polymers based on tertiary amine groups have
been studied extensively as a class of dual-responsive polymers. In particular, their …

Double-network hydrogels including enzymatically crosslinked poly-(2-alkyl-2-oxazoline) s for 3D bioprinting of cartilage-engineering constructs

L Trachsel, C Johnbosco, T Lang, EM Benetti… - …, 2019 - ACS Publications
Double-network (DN) hydrogels are fabricated from poly (2-ethyl-2-oxazoline)(PEOXA)–
peptide conjugates, which can be enzymatically crosslinked in the presence of Sortase A …

Next generation hemostatic materials based on NHS-ester functionalized poly (2-oxazoline) s

MA Boerman, E Roozen… - …, 2017 - ACS Publications
In order to prevent hemorrhage during surgical procedures, a wide range of hemostatic
agents have been developed. However, their efficacy is variable; hemostatic devices that …

Visualization and design of the functional group distribution during statistical copolymerization

PHM Van Steenberge, O Sedlacek… - Nature …, 2019 - nature.com
Even though functional copolymers with a low percentage of functional comonomer units (up
to 20 mol%) are widely used, for instance for the development of polymer therapeutics and …

Functional nanoassemblies of cyclic polymers show amplified responsiveness and enhanced protein-binding ability

L Trachsel, M Romio, B Grob, M Zenobi-Wong… - ACS …, 2020 - ACS Publications
The physicochemical properties of cyclic polymer adsorbates are significantly influenced by
the steric and conformational constraints introduced during their cyclization. These translate …

Molecularly imprinted polymers with enhanced selectivity based on 4-(aminomethyl) pyridine-functionalized poly (2-oxazoline) s for detecting hazardous herbicide …

M Cegłowski, YW Marien, S Smeets… - Chemistry of …, 2021 - ACS Publications
The detection of hazardous compounds is of importance to control (drinking) water quality.
Here, we report the development of poly (2-oxazoline)-based molecularly imprinted …

[HTML][HTML] Recent developments in synthetic approaches for macromolecular prodrugs

J Alex, C Weber, C Guerrero-Sanchez… - Progress in Polymer …, 2024 - Elsevier
In the last decades, nanoscale drug delivery systems have gained great attention partly due
to their ability to improve the bioavailability of water insoluble drugs. To this end, the general …