Necrosis is an overarching term that describes cell death modalities caused by (extreme)
adverse conditions in which cells lose structural integrity. A guaranteed consequence of …

Gelsolin, an actin-depolymerizing protein expressed both in extracellular fluids and in the
cytoplasm of a majority of human cells, has been recently implicated in a variety of both …

The COVID-19 pandemic is an unprecedented global challenge, and point-of-care
diagnostic classifiers are urgently required. Here, we present a platform for ultra-high …

Abstract Gelsolin, a Ca2+‐regulated actin filament severing, capping, and nucleating
protein, is an ubiquitous, multifunctional regulator of cell structure and metabolism. More …

Observational studies in chronic kidney disease (CKD) populations consistently have shown
the strong mortality-predictability of such markers of protein-energy wasting (PEW) as …

In response to emerging infectious diseases, such as the recent pandemic of coronavirus
disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 …

The factors that influence survival during severe infection are unclear. Extracellular
chromatin drives pathology, but the mechanisms enabling its accumulation remain elusive …

Molecular biomarkers in blood are needed to aid the early diagnosis and clinical
assessment of glioblastoma (GBM). Here, in order to identify biomarker candidates in …

Plasma gelsolin levels significantly decline in several disease conditions, since gelsolin gets
scavenged when it depolymerizes and caps filamentous actin released in the circulation …

Gelsolin (GSN), one of the most abundant actin-binding proteins, is involved in cell motility,
shape and metabolism. As a member of the GSN superfamily, GSN is a highly structured …