Advances in drug delivery systems, challenges and future directions

TC Ezike, US Okpala, UL Onoja, CP Nwike, EC Ezeako… - Heliyon, 2023 - cell.com
Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …

Application of hyaluronic acid as carriers in drug delivery

G Huang, H Huang - Drug delivery, 2018 - Taylor & Francis
Hyaluronic acid has good biocompatibility, biodegradability, and nonimmunogenicity. In
addition, it has the ability to recognize specific receptors that are overexpressed on the …

Hyaluronic acid nanofiber mats loaded with antimicrobial peptide towards wound dressing applications

Q Yang, Z Xie, J Hu, Y Liu - Materials Science and Engineering: C, 2021 - Elsevier
Chronic wounds are highly susceptible to bacterial infections. Previously, we loaded a
natural antimicrobial peptide of low cost and high safety, ε-polylysine (EPL), into the …

Nanotechnology-based biopolymeric oral delivery platforms for advanced cancer treatment

VT Chivere, PPD Kondiah, YE Choonara, V Pillay - Cancers, 2020 - mdpi.com
Routes of drug administration and their corresponding physiochemical characteristics play
major roles in drug therapeutic efficiency and biological effects. Each route of delivery has …

CD44 regulates cell proliferation, migration, and invasion via modulation of c-Src transcription in human breast cancer cells

KS Nam, S Oh, K Lee, S Yoo, I Shin - Cellular signalling, 2015 - Elsevier
CD44 was recently identified as a cancer initiation marker on the cell membrane. The
cytoplasmic tail of CD44 is known to bind ERM (ezrin, radixin, moesin) proteins, cytoskeletal …

[HTML][HTML] Breaking barriers in cancer management: The promising role of microsphere conjugates in cancer diagnosis and therapy

A Gupta, S Kulkarni, S Soman, M Saha… - International Journal of …, 2024 - Elsevier
Cancer is a significant worldwide health concern, and there is a demand for ongoing
breakthroughs in treatment techniques. Microspheres are among the most studied drug …

Hyaluronan: Sources, Structure, Features and Applications

K Valachová, ME Hassan, L Šoltés - Molecules, 2024 - mdpi.com
Hyaluronan (HA) is a non-sulfated glycosaminoglycan that is present in a variety of body
tissues and organs. Hyaluronan has a wide range of biological activities that are frequently …

[PDF][PDF] Advancing healthcare: Exploring recent innovations in drug delivery systems

M Hoque, MS Hossain, T Akram… - International Journal of …, 2023 - researchgate.net
It has been demonstrated that drug delivery systems can enhance therapeutic efficacy,
decrease toxicity, increase patient compliance, and even enable whole new medical …

CD44 in Bone Metastasis Development: A Key Player in the Fate Decisions of the Invading Cells?

NS Zer, N Ben-Ghedalia-Peled, LA Gheber… - Clinical & Experimental …, 2023 - Springer
A participant in key developmental processes, the adhesion glycoprotein CD44 is also
expressed in several types of malignancies and can promote metastasis. In addition, the …

Polymeric nanoparticles

BM Jarai, EL Kolewe, ZS Stillman, N Raman… - Nanoparticles for …, 2020 - Elsevier
Polymers, a diverse class of materials composed of repeating units called monomers, are an
essential tool of drug delivery. Polymer nanoparticles may possess a wide variety of …