Role of Toll‐like receptors in the pathogenesis of COVID‐19

S Khanmohammadi, N Rezaei - Journal of medical virology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), has led to a pandemic since March 2020. The …

A systematic review of pregnant women with COVID-19 and their neonates

M Mirbeyk, A Saghazadeh, N Rezaei - Archives of gynecology and …, 2021 - Springer
Abstract Background In December 2019, a novel coronavirus disease (COVID-19) emerged
in Wuhan, China, with an incredible contagion rate. However, the vertical transmission of …

The acid sphingomyelinase/ceramide system in COVID-19

J Kornhuber, N Hoertel, E Gulbins - Molecular Psychiatry, 2022 - nature.com
Acid sphingomyelinase (ASM) cleaves sphingomyelin into the highly lipophilic ceramide,
which forms large gel-like rafts/platforms in the plasma membrane. We showed that SARS …

On inflammatory hypothesis of depression: what is the role of IL-6 in the middle of the chaos?

E Roohi, N Jaafari, F Hashemian - Journal of neuroinflammation, 2021 - Springer
Many patients with major depressive disorder (MDD) are reported to have higher levels of
multiple inflammatory cytokines including interleukin 6 (IL-6). Recent studies both pre …

Thyroid and COVID-19: a review on pathophysiological, clinical and organizational aspects

G Lisco, A De Tullio, E Jirillo, VA Giagulli… - Journal of …, 2021 - Springer
Background Thyroid dysfunction has been observed in patients with COVID-19, and
endocrinologists are requested to understand this clinical issue. Pandemic-related …

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets

A Fodor, B Tiperciuc, C Login… - Oxidative medicine …, 2021 - Wiley Online Library
The outbreak of the COVID‐19 pandemic represents an ongoing healthcare emergency
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …

The role of IL-6 and IL-6 blockade in COVID-19

N Potere, A Batticciotto, A Vecchié… - Expert review of …, 2021 - Taylor & Francis
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …

Computational drug discovery and repurposing for the treatment of COVID-19: A systematic review

K Mohamed, N Yazdanpanah, A Saghazadeh… - Bioorganic …, 2021 - Elsevier
Background Since the beginning of the novel coronavirus (SARS-CoV-2) disease outbreak,
there has been an increasing interest in finding a potential therapeutic agent for the disease …

[HTML][HTML] Metabolic syndrome and COVID-19

H Yanai - Cardiology research, 2020 - ncbi.nlm.nih.gov
Recent studies showed that comorbidities such as diabetes, hypertension and obesity
contribute to severe and worse outcomes of coronavirus disease 2019 (COVID-19) …

Ivermectin shows clinical benefits in mild to moderate COVID19: a randomized controlled double-blind, dose-response study in Lagos

OE Babalola, CO Bode, AA Ajayi… - … Journal of Medicine, 2021 - academic.oup.com
Introduction In vitro studies have shown the efficacy of Ivermectin (IV) to inhibit the SARS—
CoV-2 viral replication, but questions remained as to in-vivo applications. We set out to …