The GH/IGF-1 axis in chronic heart failure

M Arcopinto, E Bobbio, E Bossone… - … Metabolic & Immune …, 2013 - ingentaconnect.com
The classic model of Chronic Heart Failure (CHF) is rooted in the overexpression of
neurohormonal molecules. To complement this paradigm, increasing evidence indicates …

Growth hormone therapy in heart failure

A Salzano, AM Marra, R D'Assante… - Heart failure …, 2018 - heartfailure.theclinics.com
Despite considerable improvement in the management of heart failure (HF), unsustainable
levels of morbidity and mortality coupled with an increasing economic and social burden …

[HTML][HTML] A radiomics-based model with the potential to differentiate growth hormone deficiency and idiopathic short stature on sella MRI

T Lee, K Song, B Sohn, J Eom, SS Ahn… - Yonsei Medical …, 2022 - ncbi.nlm.nih.gov
Purpose We hypothesized that a radiomics approach could be employed to classify children
with growth hormone deficiency (GHD) and idiopathic short stature (ISS) on sella magnetic …

Growth hormone as biomarker in heart failure

AM Marra, E Bobbio, R D'Assante… - Heart Failure …, 2018 - heartfailure.theclinics.com
The neuro-hormonal model has radically changed our understanding of chronic heart failure
(CHF) pathophysiology and represented the theoretic background for the implementation of …

The impairment of the Growth Hormone/Insulin-like growth factor 1 (IGF-1) axis in heart failure: A possible target for future therapy

L Piccioli, M Arcopinto, A Salzano… - … Archives for Chest …, 2018 - monaldi-archives.org
Hormonal abnormalities are quite common in chronic heart failure (CHF). The most studied
hormonal axis in CHF is the impairment of Growth Hormone (GH)/Insulin Growth Factor-1 …

Hormonal replacement therapy in heart failure: focus on growth hormone and testosterone

A Salzano, R D'Assante, M Lander… - Heart Failure …, 2019 - heartfailure.theclinics.com
To date, the mainstay of heart failure (HF) treatment is considered the counteraction of
neurohormonal overactivation. 1 Indeed, according to the namesake pathophysiological …

Serum insulin-like growth factor-1 as a potential prognostic biomarker for heart failure with reduced ejection fraction: a meta-analysis

T Liu, F Li, Y Fei, F Sun, M Chen, X Tian… - Frontiers in …, 2024 - frontiersin.org
Background Most studies have indicated that peripheral insulin-like growth levels factor-1
(IGF-1) is valuable in diagnosing heart failure, although the results have been inconsistent …

Effect of growth hormone deficiency on brain MRI findings among children with growth restrictions

F Naderi, SR Eslami, SA Mirak, M Khak… - Journal of Pediatric …, 2015 - degruyter.com
Objectives: Growth hormone deficiency (GHD) is a major problem among children with short
stature. In this study, the role of brain magnetic resonance imaging (MRI) in defining the …

Intravoxel incoherent motion in normal pituitary gland: initial study with turbo spin-echo diffusion-weighted imaging

K Kamimura, M Nakajo, Y Fukukura… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: DWI with conventional single-shot EPI of the pituitary
gland is hampered by strong susceptibility artifacts. Our purpose was to evaluate the …

High-resolution heavily T2-weighted magnetic resonance imaging for evaluation of the pituitary stalk in children with ectopic neurohypophysis

I El Sanharawi, L Tzarouchi, L Cardoen, L Martinerie… - Pediatric …, 2017 - Springer
Background In anterior pituitary deficiency, patients with non visible pituitary stalk have more
often multiple deficiencies and persistent deficiency than patients with visible pituitary stalk …