Adrenocortical carcinoma (ACC) is a rare endocrine malignancy arising from the adrenal
cortex often with unexpected biological behavior. It can occur at any age, with two peaks of …

Background Metastasis is the leading cause of death in patients with osteosarcoma. Some
of these patients fail to respond to chemotherapy and die of metastasis within a short period …

Renal interstitial fibrosis is the pathological basis of end-stage renal disease, in which the
heterogeneity of macrophages in renal microenvironment plays an important role. However …

Oral submucous fibrosis (OSF) is a potentially malignant disorder of the oral mucosa;
however, whether and how the fibrotic matrix of OSF is involved in the malignant …

Summary the evolving genomic landscape of ACC requires target validation in terms of
prognostic and predictive value within scientific consortia. Although the existing multiple …

Endothelial-to-mesenchymal transition (EndMT) is the biological process through which
endothelial cells transdifferentiate into mesenchymal cells. During embryo development …

To investigate the role and potential mechanism of serine/threonine kinase 36 (STK36) in
docetaxel resistance-prostate cancer (PCa). The expression of STK36 in PCa and the …

Background To analyze the inhibitory effects of Asiaticoside (ATS) on the epithelial-
mesenchymal transition (EMT) and stem cell-like properties of a pancreatic cancer cell line …

Renal tubular epithelial–mesenchymal transition (EMT) is the main pathological change in
diabetic renal tubulointerstitial fibrosis. Mounting evidence indicates that the inhibitor of …

Background Recurrence and distant metastasis are still the main factors leading to treatment
failure for malignant tumors including nasopharyngeal carcinoma (NPC). Therefore …