Junctional epithelium and hemidesmosomes: Tape and rivets for solving the “percutaneous device dilemma” in dental and other permanent implants

NG Fischer, C Aparicio - Bioactive materials, 2022 - Elsevier
The percutaneous device dilemma describes etiological factors, centered around the
disrupted epithelial tissue surrounding non-remodelable devices, that contribute to rampant …

[HTML][HTML] The bone anchored prostheses for amputees–Historical development, current status, and future aspects

Y Li, L Felländer-Tsai - Biomaterials, 2021 - Elsevier
In the past 50 years, bone anchored prostheses have evolved from a concept for
experimental treatment to a rapidly developing area in orthopedics and traumatology. Up to …

A novel osseointegrated percutaneous prosthetic system for the treatment of patients with transfemoral amputation: A prospective study of 51 patients

R Brånemark, Ö Berlin, K Hagberg… - The bone & joint …, 2014 - boneandjoint.org.uk
Patients with transfemoral amputation (TFA) often experience problems related to the use of
socket-suspended prostheses. The clinical development of osseointegrated percutaneous …

Biological sealing and integration of a fibrinogen-modified titanium alloy with soft and hard tissues in a rat model

X Wang, X Lei, Y Yu, S Miao, J Tang, Y Fu, K Ye… - Biomaterials …, 2021 - pubs.rsc.org
Percutaneous or transcutaneous devices are important and unique, and the corresponding
biological sealing at the skin-implant interface is the key to their long-term success. Herein …

Immunomodulation‐based strategy for improving soft tissue and metal implant integration and its implications in the development of metal soft tissue materials

R Liu, S Chen, P Huang, G Liu, P Luo… - Advanced Functional …, 2020 - Wiley Online Library
The difficulties associated with metal implants and soft tissue integration have significantly
affected the applications of metal implants in soft‐tissue‐related areas. Prompted by the …

Soft and Hard Tissue Integration around Percutaneous Bone-Anchored Titanium Prostheses: Toward Achieving Holistic Biointegration

S Shrivas, H Samaur, V Yadav… - ACS Biomaterials Science …, 2024 - ACS Publications
A holistic biointegration of percutaneous bone-anchored metallic prostheses with both hard
and soft tissues dictates their longevity in the human body. While titanium (Ti) has nearly …

[HTML][HTML] E-cadherin biomaterials reprogram collective cell migration and cell cycling by forcing homeostatic conditions

K Suh, YK Cho, IB Breinyn, DJ Cohen - Cell Reports, 2024 - cell.com
Cells attach to the world through either cell-extracellular matrix adhesion or cell-cell
adhesion, and traditional biomaterials imitate the matrix for integrin-based adhesion …

[HTML][HTML] Comparison In Vitro Study on the Interface between Skin and Bone Cell Cultures and Microporous Titanium Samples Manufactured with 3D Printing …

M Shevtsov, E Pitkin, SE Combs, GVD Meulen… - Nanomaterials, 2024 - mdpi.com
Percutaneous implants osseointegrated into the residuum of a person with limb amputation
need to provide mechanical stability and protection against infections. Although significant …

The first FDA approved early feasibility study of a novel percutaneous bone anchored prosthesis for transfemoral amputees: a prospective 1-year follow-up cohort …

S Sinclair, JP Beck, J Webster, J Agarwal… - Archives of Physical …, 2022 - Elsevier
Objective Evaluate the safety and efficacy of a novel press-fit bone-anchored prosthesis in
an FDA approved study. Design Single-center, prospective 1-year follow-up cohort study of …

Skin adhesion to the percutaneous component of direct bone anchored systems: systematic review on preclinical approaches and biomaterials

M Sartori, V Borsari, M Maglio, S Brogini… - Biomaterials …, 2021 - pubs.rsc.org
Nowadays, direct bone anchored systems are an increasingly adopted approach in the
therapeutic landscape for amputee patients. However, the percutaneous nature of these …