The Circadian Syndrome: is the Metabolic Syndrome and much more!

P Zimmet, K Alberti, N Stern, C Bilu… - Journal of internal …, 2019 - Wiley Online Library
Abstract The Metabolic Syndrome is a cluster of cardio‐metabolic risk factors and
comorbidities conveying high risk of both cardiovascular disease and type 2 diabetes. It is …

Epigenetic programming, early life nutrition and the risk of metabolic disease

T Block, A El-Osta - Atherosclerosis, 2017 - Elsevier
Time separates the past from the present, during this period memory are formed-written in
code and decoded to be read while other memories are erased-but when it comes to the …

Epigenetics in diabetic nephropathy, immunity and metabolism

ST Keating, JA van Diepen, NP Riksen, A El-Osta - Diabetologia, 2018 - Springer
When it comes to the epigenome, there is a fine line between clarity and confusion—walk
that line and you will discover another fascinating level of transcription control. With the …

Methyl donor micronutrients, hypothalamic development and programming for metabolic disease

R Kubant, CE Cho, E Pannia, R Hammoud… - Neuroscience & …, 2024 - Elsevier
Nutriture in utero is essential for fetal brain development through the regulation of neural
stem cell proliferation, differentiation, and apoptosis, and has a long-lasting impact on risk of …

[HTML][HTML] Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension

F Kawakami-Mori, M Nishimoto, L Reheman… - JCI insight, 2018 - ncbi.nlm.nih.gov
Maternal malnutrition, which causes prenatal exposure to excessive glucocorticoid, induces
adverse metabolic programming, leading to hypertension in offspring. In offspring of …

Influence of Parental and Offspring Dietary Behaviors on the Association of Overweight and Obesity between Two Generations: Results from a Cross-Sectional …

Q Ma, T Chen, J Liu, M Chen, D Gao, Y Li, T Ma… - Nutrients, 2022 - mdpi.com
Limited evidence exists on the influence of dietary behaviors on the association of
overweight/obesity between parents and offspring. This study aimed to investigate the …

Diet during pregnancy is implicated in the regulation of hypothalamic RNA methylation and risk of obesity in offspring

A Kaspi, I Khurana, M Ziemann… - Molecular Nutrition & …, 2018 - Wiley Online Library
Scope Early life nutrition has long‐lasting influence in adults through key mediators that
modulate epigenetic states, although the determinants involved that underlie this response …

Metabolism and chromatin dynamics in health and disease

H Rodriguez, H Rafehi, M Bhave, A El-Osta - Molecular aspects of medicine, 2017 - Elsevier
The regulation of gene expression in response to environmental and behavioural cues is
critical for many biological processes. Histone tail modifications are dynamic and, as such …

Epigenetics and ageing

N Monroy-Jaramillo, ER Vázquez-Martínez - Clinical Genetics and …, 2020 - Springer
Epigenetics is considered as a dynamic interface between the genome and the environment
and encompasses different mechanisms that regulate chromatin dynamics and gene …

[PDF][PDF] Ergebnisse der PEACHES (Programming of Enhanced Adiposity Risk in CHildhood-Early Screening)-Studie

KE Lange - docserv.uni-duesseldorf.de
Die steigende Prävalenz von Übergewicht und Adipositas im Kindes-und Jugendalter bringt
erhebliche Probleme mit weitreichenden Folgen. Daher sind bereits früh ansetzende …