▪ Abstract The lung collectins, SP-A and SP-D, are important components of the innate
immune response to microbial challenge and participate in other aspects of immune and …

Adiponectin is an adipocyte-derived hormone, which has been shown to play important
roles in the regulation of glucose and lipid metabolism. Eight mutations in human …

To recognise and respond to pathogens, germ-line encoded pattern recognition receptors
(PRRs) bind to conserved microbial structures and activate host defence systems, including …

Collectins and ficolins represent two important groups of pattern recognition molecules,
which bind to oligosaccharide structures on the surface of microorganisms, leading to the …

The surfactant‐associated proteins SP‐A and SP‐D are members of a family of host defense
lectins, designated collectins. There is increasing evidence that these pulmonary, epithelial …

Research over the last decade on the surfactant proteins SP‐A and SP‐D suggests roles
beyond surfactant lipid homeostasis, involving their participation in innate immune defence …

Pulmonary surfactant in bronchoalveolar lavage fluid (BALF) and induced sputum from
adults with stable asthma (n= 36) and healthy controls (n= 12) was analyzed for …

Soluble defense collagens form a group of secreted proteins that are primarily involved in
host defense. All defense collagens contain a globular recognition domain contiguous to a …

ABSTRACT Surfactant protein A (SP‐A) is the major protein component of pulmonary
surfactant, a material secreted by the alveolar type II cell that reduces surface tension at the …

Although the lung is protected by classic innate and adaptive immune mechanisms, another
unique local immunoregulatory system involving pulmonary surfactant is described in this …