BCS class IV drugs: Highly notorious candidates for formulation development

R Ghadi, N Dand - Journal of Controlled Release, 2017 - Elsevier
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …

Nanosponges as an emerging platform for cancer treatment and diagnosis

BHJ Gowda, MG Ahmed, MAA Almoyad… - Advanced Functional …, 2024 - Wiley Online Library
Nanosponges are unique sponge‐like carrier systems with numerous cavities and a mesh‐
like network throughout their surface. They are categorized into three types based on the …

Effect of nanovesicular surface-functionalization via chitosan and/or PEGylation on cytotoxicity of tamoxifen in induced-breast cancer model

MA Megahed, HS El-Sawy, AM Reda, FI Abd-Allah… - Life Sciences, 2022 - Elsevier
Aims The effect of surface-modification of Tamoxifen (Tam)-loaded-niosomes on drug
cytotoxicity and bio-distribution, via functionalization with chitosan and/or PEGylation, was …

[图书][B] Design and development of new nanocarriers

AM Grumezescu - 2017 - books.google.com
Design and Development of New Nanocarriers focuses on the design and development of
new nanocarriers used in pharmaceutical applications that have emerged in recent years. In …

Dual drug delivery of tamoxifen and quercetin: regulated metabolism for anticancer treatment with nanosponges

JN Lockhart, DM Stevens, DB Beezer, A Kravitz… - Journal of Controlled …, 2015 - Elsevier
We report the synthesis and encapsulation of polyester nanosponge particles (NPs) co-
loaded with tamoxifen (TAM) and quercetin (QT) to investigate the loading, release and in …

Combined MEK Inhibition and BMP2 Treatment Promotes Osteoblast Differentiation and Bone Healing in Nf1Osx−/− Mice

J de la Croix Ndong, DM Stevens… - Journal of Bone and …, 2015 - academic.oup.com
Neurofibromatosis type I (NF1) is an autosomal dominant disease with an incidence of
1/3000, caused by mutations in the NF1 gene, which encodes the RAS/GTPase‐activating …

Improvements in chemical carriers of proteins and peptides

A Bolhassani - Cell Biology International, 2019 - Wiley Online Library
The successful intracellular delivery of biologically active proteins and peptides plays an
important role for therapeutic applications. Indeed, protein/peptide delivery could overcome …

Matrices for combined delivery of proteins and synthetic molecules

KA Gilmore, MW Lampley, C Boyer, E Harth - Advanced Drug Delivery …, 2016 - Elsevier
With the increasing advancement of synergistic, multimodal approaches to influence the
treatment of infectious and non-infectious diseases, we witness the development of enabling …

Enhancing the therapeutic efficacy of tamoxifen citrate loaded span-based nano-vesicles on human breast adenocarcinoma cells

MA Kassem, MA Megahed, SK Abu Elyazid… - AAPS …, 2018 - Springer
Serious adverse effects and low selectivity to cancer cells are the main obstacles of long
term therapy with Tamoxifen (Tmx). This study aimed to develop Tmx-loaded span-based …

Cyclodextrin nanosponges in drug delivery and nanotherapeutics

RA Osmani, P Kulkarni, S Manjunatha… - Environmental …, 2018 - Springer
The drug delivery technology landscape has become highly competitive and rapidly
evolving as more and more developments in delivery systems are being integrated to …