Adult neurogenesis, glia, and the extracellular matrix
EC Cope, E Gould - Cell Stem Cell, 2019 - cell.com
In the adult mammalian hippocampus, new neurons arise from stem and progenitor cell
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …
The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments
MC Morganti-Kossmann, BD Semple, SC Hellewell… - Acta …, 2019 - Springer
This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …
of neuroinflammation in the injured brain following trauma. We summarise the literature …
Hippocampal neurophysiologic changes after mild traumatic brain injury and potential neuromodulation treatment approaches
Traumatic brain injury (TBI) is the leading cause of death and disability in individuals below
age 45, and five million Americans live with chronic disability as a result. Mild TBI (mTBI) …
age 45, and five million Americans live with chronic disability as a result. Mild TBI (mTBI) …
New neurons in adult brain: distribution, molecular mechanisms and therapies
Abstract “Are new neurons added in the adult mammalian brain?”“Do neural stem cells
activate following CNS diseases?”“How can we modulate their activation to promote …
activate following CNS diseases?”“How can we modulate their activation to promote …
Traumatic brain injury causes aberrant migration of adult-born neurons in the hippocampus
Traumatic brain injury (TBI) promotes neural stem/progenitor cell (NSC) proliferation in an
attempt to initiate innate repair mechanisms. However, all immature neurons in the CNS are …
attempt to initiate innate repair mechanisms. However, all immature neurons in the CNS are …
Enhanced dentate neurogenesis after brain injury undermines long-term neurogenic potential and promotes seizure susceptibility
EJ Neuberger, B Swietek, L Corrubia, A Prasanna… - Stem cell reports, 2017 - cell.com
Hippocampal dentate gyrus is a focus of enhanced neurogenesis and excitability after
traumatic brain injury. Increased neurogenesis has been proposed to aid repair of the …
traumatic brain injury. Increased neurogenesis has been proposed to aid repair of the …
Impact of traumatic brain injury on neurogenesis
LB Ngwenya, SC Danzer - Frontiers in neuroscience, 2019 - frontiersin.org
New neurons are generated in the hippocampal dentate gyrus from early development
through adulthood. Progenitor cells and immature granule cells in the subgranular zone are …
through adulthood. Progenitor cells and immature granule cells in the subgranular zone are …
The potential of stem cells in treatment of traumatic brain injury
NM Weston, D Sun - Current neurology and neuroscience reports, 2018 - Springer
Abstract Purpose of Review Traumatic brain injury (TBI) is a global public health concern,
with limited treatment options available. Despite improving survival rate after TBI, treatment …
with limited treatment options available. Despite improving survival rate after TBI, treatment …
The genetic basis of inter-individual variation in recovery from traumatic brain injury
D Cortes, MF Pera - NPJ regenerative medicine, 2021 - nature.com
Traumatic brain injury (TBI) is one of the leading causes of death among young people, and
is increasingly prevalent in the aging population. Survivors of TBI face a spectrum of …
is increasingly prevalent in the aging population. Survivors of TBI face a spectrum of …
Traumatic brain injury and hippocampal neurogenesis: Functional implications
In the adult brain, self-renewing radial-glia like (RGL) progenitor cells have been shown to
reside in the subventricular zone and the subgranular zone of the hippocampus. A large …
reside in the subventricular zone and the subgranular zone of the hippocampus. A large …