Ewing sarcoma, a highly aggressive bone and soft-tissue cancer, is considered a prime
example of the paradigms of a translocation-positive sarcoma: a genetically rather simple …

Ewing's Sarcoma Ewing's sarcoma, an aggressive cancer of bone and soft tissue, primarily
affects children and young adults. A t (11; 22) translocation is noted in 85 to 90% of cases …

Highlights•This Clinical Practice Guideline provides key recommendations on the
management of bone sarcomas.•Recommendations have been agreed following a …

Primary bone tumours are rare, accounting for< 0.2% of malignant neoplasms registered in
the EUROCARE (European Cancer Registry based study on survival and care of cancer …

The NCCN Guidelines for Bone Cancer provide interdisciplinary recommendations for
treating chordoma, chondrosarcoma, giant cell tumor of bone, Ewing sarcoma, and …

Purpose To improve the poor prognosis of patients with primary disseminated multifocal
Ewing sarcomas (PDMES) with a dose-intense treatment concept. Patients and Methods …

One explanation for the relative lack of progress in treating cancer in adolescents and young
adults is that the biology of malignant diseases in this age group is different than in younger …

Purpose The US population-based cancer registry Surveillance, Epidemiology, and End
Results (SEER) database provides an opportunity to evaluate the incidence and survival …

This document is an update of the British Sarcoma Group guidelines (2016) and provides a
reference standard for the clinical care of UK patients with primary malignant bone tumours …

Purpose For over 30 years, the place of consolidation high-dose chemotherapy in Ewing
sarcoma (ES) has been controversial. A randomized study was conducted to determine …