Identification of cis-acting replication element in VP2-encoding region of Senecavirus A genome

H Meng, X Wang, L Wang, Q Wang, L Zhu, Y Sang… - Veterinary …, 2023 - Elsevier
Picornavirus possesses one positive-sense, single-stranded RNA genome, in which a cis-
acting replication element (cre) is located. The cre is a stem-loop structure that harbors a …

The construction and immunogenicity analyses of a recombinant pseudorabies virus with senecavirus A VP2 protein coexpression

Q Tao, L Zhu, L Xu, Y Yang, Y Zhang, Z Liu… - Microbiology …, 2023 - Am Soc Microbiol
Senecavirus A (SVA)-associated porcine idiopathic vesicular disease (PIVD) and
pseudorabies (PR) are highly contagious swine diseases that pose a significant threat to the …

Development and characterization of a recombinant Senecavirus A expressing enhanced green fluorescent protein

W Huang, Y Chen, T Xu, T Xiong, Y Lv, D Liu… - Frontiers in …, 2024 - frontiersin.org
Introduction Senecavirus A (SVA), belonging to the genus Senecavirus in the family
Picornaviridae, is an emerging pathogen causing vesicular disease in pigs. The main …

[HTML][HTML] Phylogeographic Characterizations of Recent (2015–2023) Senecavirus A Isolates from Canada

K Hole, O Vernygora, K Handel, M Nebroski, O Lung… - Viruses, 2025 - mdpi.com
Senecavirus A (SVA) continues to cause vesicular lesions in swine in Canada and many
regions worldwide. Since the vesicular lesions caused by SVA are similar to those caused …

Development and optimization of a double antigen sandwich ELISA detecting for Senecavirus A antibodies based on VP2 protein

J Chen, Z Shi, J Luo, C Jia, X Zhang, J Wei… - Microbiology …, 2024 - journals.asm.org
Senecavirus A (SVA) is an emerging viral pathogen that threatens the global swine industry
significantly. The major clinical symptoms of SVA-infected animals are vesicular lesions, but …

Substitutions of stem-loop subdomains in internal ribosome entry site of Senecavirus A: Impacts on rescue of sequence-modifying viruses

Q Wang, J Wang, L Zhang, X Duan, L Zhu… - Journal of Integrative …, 2024 - Elsevier
Senecavirus A (SVA) has a positive-sense, single-stranded RNA genome. Its 5'untranslated
region harbors an internal ribosome entry site (IRES), comprising ten larger or smaller stem …

[HTML][HTML] A putative wild-type or wild-type-like hairpin structure is required within 3′ untranslated region of Senecavirus A for virus replication

D Zhao, Q Wang, M Wang, L Lyu, S Liu, Y Jiang… - Virology, 2023 - Elsevier
Abstract The 3′ untranslated region (UTR) of Senecavirus A (SVA) was predicted to harbor
two hairpin structures, hairpin-I and-II. The former is composed of two internal loops, one …

RNA recombination: non-negligible factor for preventing emergence or reemergence of Senecavirus A

Y Li, T Liu, Y Zhang, X Duan, F Liu - Frontiers in Veterinary Science, 2024 - frontiersin.org
As an emerging virus, Senecavirus A (SVA) induces the vesicular disease in pigs. Clinical
cases initially show mild signs characterized by lethargy and lameness, usually followed by …

[HTML][HTML] Translation of Senecavirus A polyprotein is initiated from the IRES-proximal initiation codon

Q Wang, D Zhao, L Wang, Y Sang, H Meng, Q Wang… - Virology, 2023 - Elsevier
To clarify whether Senecavirus A (SVA) has the potential of alternative translation, an extra
G residue was inserted into an SVA cDNA clone, resultantly generating an “AUGAUG” motif …

Novel introductions of human-origin H3N2 Influenza viruses in Swine, Chile

BM Agüero, N Ariyama, F Berrios, N Enciso… - Frontiers in Veterinary …, 2025 - frontiersin.org
Influenza A virus (IAV) continuously threatens animal and public health globally, with swine
serving as a crucial reservoir for viral reassortment and evolution. In Chile, H1N2 and H3N2 …