Role of natural products for the treatment of Alzheimer's disease

T Noori, AR Dehpour, A Sureda… - European journal of …, 2021 - Elsevier
Negative psychological and physiological consequences of neurodegenerative disorders
represent a high social and health cost. Among the neurodegenerative disorders …

[HTML][HTML] Amyloid cascade hypothesis for the treatment of alzheimer's disease: progress and challenges

T Wu, D Lin, Y Cheng, S Jiang, MW Riaz, N Fu… - Aging and …, 2022 - ncbi.nlm.nih.gov
The amyloid cascade hypothesis has always been a research focus in the therapeutic field
of Alzheimer's disease (AD) since it was put forward. Numerous researchers attempted to …

Polyphenols in Alzheimer's disease and in the gut–brain axis

VP Reddy, P Aryal, S Robinson, R Rafiu, M Obrenovich… - Microorganisms, 2020 - mdpi.com
Polyphenolic antioxidants, including dietary plant lignans, modulate the gut–brain axis,
which involves transformation of these polyphenolic compounds into physiologically active …

Marine cyanobacteria: A source of lead compounds and their clinically-relevant molecular targets

LT Tan, MY Phyo - Molecules, 2020 - mdpi.com
The prokaryotic filamentous marine cyanobacteria are photosynthetic microbes that are
found in diverse marine habitats, ranging from epiphytic to endolithic communities. Their …

[PDF][PDF] Natural products for attenuating Alzheimer's disease: A narrative review

NT Abdulaziz, FY Al-bazzaz… - Eurasian Chemical …, 2023 - researchgate.net
Alzheimer's disease (AD) is an irreversible (may be fatal) neurological ailment that affects an
increasing number of elderly people. According to research, AD is the most frequent cause …

[HTML][HTML] The potential roles of ATF family in the treatment of Alzheimer's disease

T Yang, Y Zhang, L Chen, ER Thomas, W Yu… - Biomedicine & …, 2023 - Elsevier
Activating transcription factors, ATFs, is a family of transcription factors that activate gene
expression and transcription by recognizing and combining the cAMP response element …

Microorganism-derived molecules as enzyme inhibitors to target Alzheimer's diseases pathways

TH Nguyen, SL Wang, VB Nguyen - Pharmaceuticals, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia. It increases the risk of other
serious diseases and causes a huge impact on individuals, families, and socioeconomics …

Molecular level insight into the benefit of myricetin and dihydromyricetin uptake in patients with Alzheimer's diseases

M Liu, H Guo, Z Li, C Zhang, X Zhang… - Frontiers in Aging …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease with a high incidence rate and
complicated pathogenesis. Currently, all anti-AD drugs treat the symptoms of the disease …

BACE1 inhibitors for Alzheimer's Disease: current challenges and Future perspectives

JRM Coimbra, R Resende… - Journal of …, 2024 - journals.sagepub.com
Disease-modifying therapies (DMT) for Alzheimer's disease (AD) are highly longed-for. In
this quest, anti-amyloid therapies take center stage supported by genetic facts that highlight …

Implications of the human gut–brain and gut–cancer axes for future nanomedicine

I Javed, X Cui, X Wang, M Mortimer, N Andrikopoulos… - ACS …, 2020 - ACS Publications
Recent clinical and pathological evidence have implicated the gut microbiota as a nexus for
modulating the homeostasis of the human body, impacting conditions from cancer and …