[HTML][HTML] Optical coherence tomography angiography

RF Spaide, JG Fujimoto, NK Waheed, SR Sadda… - Progress in retinal and …, 2018 - Elsevier
Optical coherence tomography (OCT) was one of the biggest advances in ophthalmic
imaging. Building on that platform, OCT angiography (OCTA) provides depth resolved …

Rethinking the initial changes in subarachnoid haemorrhage: focusing on real-time metabolism during early brain injury

Y Chen, I Galea, RL Macdonald, GKC Wong… - …, 2022 - thelancet.com
Over the last two decades, neurological researchers have uncovered many
pathophysiological mechanisms associated with subarachnoid haemorrhage (SAH), with …

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models

JC Cruz Hernández, O Bracko, CJ Kersbergen… - Nature …, 2019 - nature.com
Cerebral blood flow (CBF) reductions in Alzheimer's disease patients and related mouse
models have been recognized for decades, but the underlying mechanisms and resulting …

The blood–brain barrier and the neurovascular unit in subarachnoid hemorrhage: molecular events and potential treatments

P Solár, A Zamani, K Lakatosová, M Joukal - Fluids and Barriers of the …, 2022 - Springer
The response of the blood–brain barrier (BBB) following a stroke, including subarachnoid
hemorrhage (SAH), has been studied extensively. The main components of this reaction are …

Role of platelets in the pathogenesis of delayed injury after subarachnoid hemorrhage

A Dienel, P Kumar T, SL Blackburn… - Journal of Cerebral …, 2021 - journals.sagepub.com
Aneurysmal subarachnoid hemorrhage (aSAH) patients develop delayed cerebral ischemia
and delayed deficits (DCI) within 2 weeks of aneurysm rupture at a rate of approximately …

Disturbed microcirculation and hyperaemic response in a murine model of systemic inflammation

SK Fruekilde, CJ Bailey… - Journal of Cerebral …, 2022 - journals.sagepub.com
Systemic inflammation affects cognitive functions and increases the risk of dementia. This
phenomenon is thought to be mediated in part by cytokines that promote neuronal survival …

Antibody-based in vivo leukocyte label for two-photon brain imaging in mice

LD Faulhaber, O D'Costa, AY Shih, J Gust - Neurophotonics, 2022 - spiedigitallibrary.org
Significance: To study leukocyte-endothelial interactions in a living system, robust and
specific leukocyte labeling techniques are needed for in vivo two-photon microscopy of the …

Microvascular flow abnormalities associated with retinal vasculitis: a potential of mechanism of retinal injury

RF Spaide - Retina, 2017 - journals.lww.com
Purpose: To investigate the structural optical coherence tomography and related
microvascular flow characteristics in eyes with retinal vasculitis. Methods: Regions involved …

Characteristics of MRI findings after subarachnoid hemorrhage and D-dimer as a predictive value for early brain injury

M Hokari, D Shimbo, K Uchida, M Gekka… - Journal of Stroke and …, 2022 - Elsevier
Background The pathological mechanisms of early brain injury (EBI) have remained
obscure. Several studies have reported on the neuroradiological findings of EBI. However …

Inotropic support against early brain injury improves cerebral hypoperfusion and outcomes in a murine model of subarachnoid hemorrhage

T Mutoh, T Mutoh, K Nakamura, K Sasaki… - Brain Research …, 2017 - Elsevier
Early brain injury/ischemia is a recent therapeutic target that contributes to triggering
delayed cerebral ischemia (DCI) in the setting of subarachnoid hemorrhage (SAH). This …