Oxidation chemistry using enzymes is approaching maturity and practical applicability in
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …

Flavin-dependent monooxygenases catalyze a wide variety of chemo-, regio-and
enantioselective oxygenation reactions. As such, they are involved in key biological …

Flavoprotein monooxygenases (FPMOs) are single-or two-component enzymes that
catalyze a diverse set of chemo-, regio-and enantioselective oxyfunctionalization reactions …

Prenylated indole alkaloids featuring spirooxindole rings possess a 3 R or 3 S carbon
stereocenter, which determines the bioactivities of these compounds. Despite the …

Enzyme gewinnen immer mehr Bedeutung als Katalysatoren für organische
Oxidationsreaktionen. Mit Oxidoreduktasen stehen dem Chemiker vielseitige Werkzeuge für …

White-rot fungi (WRF) are the most efficient lignin-degrading organisms in nature. However,
their capacity to use lignin-related aromatic compounds, such as 4-hydroxybenzoate, as …

External flavoprotein monooxygenases comprise a group of flavin-dependent
oxidoreductases that catalyze the insertion of one atom of molecular oxygen into an organic …

Flavoprotein monooxygenases catalyze reactions, including hydroxylation and epoxidation,
involved in the catabolism, detoxification, and biosynthesis of natural substrates and …

Hydroxybenzoate 3-hydroxylase (PHBH) is the most extensively studied group A
flavoprotein monooxygenase (FPMO). PHBH is almost exclusively found in prokaryotes …

Abstract Kynurenine-3-monooxygenase (KMO) is a key FAD-dependent enzyme of
tryptophan metabolism. In animal models, KMO inhibition has shown benefit in …