Cell type-specific roles of NF-κB linking inflammation and thrombosis

M Mussbacher, M Salzmann, C Brostjan… - Frontiers in …, 2019 - frontiersin.org
The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

The complexity of NF-κB signaling in inflammation and cancer

B Hoesel, JA Schmid - Molecular cancer, 2013 - Springer
The NF-κB family of transcription factors has an essential role in inflammation and innate
immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …

Engineering bioactive M2 macrophage‐polarized, anti‐inflammatory, miRNA‐based liposomes for functional muscle repair: From exosomal mechanisms to …

Z Luo, B Qi, Y Sun, Y Chen, J Lin, H Qin, N Wang… - Small, 2022 - Wiley Online Library
Severe inflammation and myogenic differentiation disorder are the major obstacles to
skeletal muscle healing after injury. MicroRNAs (miRNAs) play an important role as …

MicroRNAs in the pathogenesis of hepatocellular carcinoma: A review

A Morishita, K Oura, T Tadokoro, K Fujita, J Tani… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

Occult HBV infection

G Raimondo, T Pollicino - Hepatitis B virus in human diseases, 2016 - Springer
The long-lasting persistence of HBV genomes in the liver (and in some cases also in the
serum) of HBsAg negative subjects is termed occult HBV infection (OBI). This peculiar …

Transcriptional regulation during aberrant activation of NF-κB signalling in cancer

K Deka, Y Li - Cells, 2023 - mdpi.com
The NF-κB signalling pathway is a major signalling cascade involved in the regulation of
inflammation and innate immunity. It is also increasingly recognised as a crucial player in …

Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action

SC Miller, R Huang, S Sakamuru, SJ Shukla… - Biochemical …, 2010 - Elsevier
Nuclear factor-kappa B (NF-κB) is a transcription factor that plays a critical role across many
cellular processes including embryonic and neuronal development, cell proliferation …

RAS/RAF/MEK/ERK, PI3K/PTEN/AKT/mTORC1 and TP53 pathways and regulatory miRs as therapeutic targets in hepatocellular carcinoma

SM Akula, SL Abrams, LS Steelman… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Hepatocellular carcinoma (HCC) is a significant problem globally because of
viral infections and the increasing incidence of obesity and fatty liver disease. However, it is …

Interplay between reactive oxygen species and microRNAs in cancer

J He, BH Jiang - Current pharmacology reports, 2016 - Springer
As both reactive oxygen species (ROS) production and microRNA expression signature
have been associated with tumor development, progression, metastasis, and therapeutic …

Inflammatory diseases and growth: effects on the GH–IGF axis and on growth plate

F Cirillo, P Lazzeroni, C Sartori, ME Street - International Journal of …, 2017 - mdpi.com
This review briefly describes the most common chronic inflammatory diseases in childhood,
such as cystic fibrosis (CF), inflammatory bowel diseases (IBDs), juvenile idiopathic arthritis …