Essential fatty acids (EFAs), linoleic acid (LA), and α‐linolenic acid (ALA) are essential for
humans, and are freely available in the diet. Hence, EFA deficiency is extremely rare in …

Mast cells are well accepted as important sentinel cells for host defence against selected
pathogens. Their location at mucosal surfaces and ability to mobilize multiple aspects of …

Mast cells have mainly been studied in the setting of allergic disease, but the importance of
mast cells for host defence against several pathogens has now been well established. The …

Mast cells are well known for their involvement in allergic and anaphylactic reactions, during
which immunoglobulin E (IgE) receptor (FcɛRI) aggregation leads to exocytosis of the …

Mast cells are well known for their involvement in allergic and anaphylactic reactions, but
recent findings implicate them in a variety of inflammatory diseases affecting different …

Injection of mineral oils such as pristane into the peritoneal cavities of BALB/c mice results in
a chronic peritonitis associated with high tissue levels of interleukin 6 (IL-6). Here we show …

Background: Inflammation plays an important role in the pathogenesis of coronary artery
disease. We examined whether dietary supplementation with α-linolenic acid (ALA, 18: 3n …

Mast cells have historically been studied mainly in the context of allergic disease. In recent
years, we have come to understand the critical importance of mast cells in tissue remodeling …

Toll-like receptors (TLRs) are a family of pattern recognition receptors that are critical for
cellular responses to a variety of bacterial, viral, and fungal products. Mast cells are …

Prostaglandins are synthesized through the metabolism of arachidonic acid via the
cyclooxygenase pathway. There are five primary prostaglandins, PGD 2, PGE 2, PGF 2, PGI …