[HTML][HTML] Therapeutic potentials of antiviral plants used in traditional african medicine with COVID-19 in focus: a Nigerian perspective

AF Attah, AA Fagbemi, O Olubiyi… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic is caused by an infectious novel strain
of coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Identifying potential natural inhibitors of Brucella melitensis Methionyl-tRNA synthetase through an in-silico approach

AB Rowaiye, AJ Ogugua, G Ibeanu, D Bur… - PLOS Neglected …, 2022 - journals.plos.org
Background Brucellosis is an infectious disease caused by bacteria of the genus Brucella.
Although it is the most common zoonosis worldwide, there are increasing reports of drug …

In-silico and in-vitro investigation of STAT3-PIM1 heterodimeric complex: Its mechanism and inhibition by curcumin for cancer therapeutics

S Mahata, SK Behera, S Kumar, PK Sahoo… - International Journal of …, 2022 - Elsevier
The functional activity among STAT3 and PIM1, are key signaling events for cancer cell
function. Curcumin, a diarylheptanoid isolated from turmeric, effectively inhibits STAT3 …

Phytochemicals of Cocculus hirsutus deciphered SARS-CoV-2 inhibition by targeting main proteases in molecular docking, simulation, and pharmacological …

M Rajan, S Prabhakaran, JS Prusty… - Journal of …, 2023 - Taylor & Francis
The COVID-19 pandemic is spreading rapidly due to the outbreak of novel coronavirus
SARS-CoV-2 across the globe. Anti-COVID-19 drugs are urgently required in this situation …

In silico identification of potential allosteric inhibitors of the SARS-CoV-2 Helicase

A Rowaiye, O Onuh, T Asala, A Ogu, D Bur… - 2020 - chemrxiv.org
The COVID-19 pandemic ravages the globe causing unprecedented health and economic
challenges. As the world prospects for a cure, scientists are looking critically at strategic …

Preparing for the storm: mitigating the effect of SARS-CoV-2 induced hypercytokinemia

AB Rowaiye, OA Okpalefe, O Ajiroghene, OA Onuh… - 2020 - 95.179.195.156
With increasing fatalities, the COVID-19 pandemic constitutes a formidable global health
challenge. The causative agent, SARS-CoV-2 constantly tests the efficacy of the immune …