Abstract mRNA-based drugs have tremendous potential as clinical treatments, however, a
major challenge in realizing this drug class will promise to develop methods for safely …

With the development and regulatory approval of immune checkpoint inhibitors and adoptive
cell therapies, cancer immunotherapy has undergone a profound transformation over the …

Precise identification and quantification of amino acids is crucial for many biological
applications. Here we report a copper (II)-functionalized Mycobacterium smegmatis porin A …

Cancer immunogenomics is an emerging field that bridges genomics and immunology. The
establishment of large-scale genomic collaborative efforts along with the development of …

Immunotherapy includes immune checkpoint inhibitors (ICI) such as antibodies targeting
cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) or the programmed cell death …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Recent advances in neoantigen research have accelerated the development of tumor
immunotherapies, including adoptive cell therapies (ACTs), cancer vaccines and antibody …

Messenger RNA (mRNA) is now in the limelight as a powerful tool for treating various
human diseases, especially malignant tumors, thanks to the remarkable clinical outcomes of …

Simple Summary Breast cancer is the most prevalent malignancy in women. With the
improvement of medical treatment, breast cancer has become one of the solid tumors with …

Adoptive cell therapy using T cell receptor-engineered T cells (TCR-T) is a promising
approach for cancer therapy with an expectation of no significant side effects. In the human …