GnRH and its analogs are used extensively for the treatment of hormone-dependent
diseases and assisted reproductive techniques. They also have potential as novel …

In human beings, two forms of GnRH, termed GnRH-I and GnRH-II, encoded by separate
genes have been identified. Although these hormones share comparable cDNA and …

Reproduction in most fish is seasonal or periodic, and the spawning occurs in an
appropriate season to ensure maximum survival of the offspring. The sequence of …

Reproductive hormones affect all stages of life from gamete production, fertilization, fetal
development and parturition, neonatal development and puberty through to adulthood and …

GnRH (gonadotropin-releasing hormone) plays a pivotal role in the regulation of
reproduction in vertebrates through interaction with a specific receptor. Previously, we …

G protein-coupled receptors (GPCRs) represent the largest family of signal-transducing
molecules known. They convey signals for light and many extracellular regulatory …

Menstruation is the cyclic and orderly sloughing of the endometrium. In order for normal
menstruation to take place, a complex interaction between the brain, the ovaries, and the …

Abstract Gonadotropin-Releasing Hormone (GnRH) is a decapeptide responsible for the
control of the reproductive functions. It shows C-and N-terminal aminoacid modifications and …

We report the identification and characterization of two distinct GnRH receptor (GnRH-R)
subtypes, designated GnRH-R1 and GnRH-R2, in a model teleost, the medaka Oryzias …

Disorders of testicular function may have their origins in fetal or early life as a result of
abnormal development or proliferation of Sertoli cells. Failure of Sertoli cells to mature, with …