Osteoarthritis (OA) is a disabling condition that affects billions of people worldwide and
places a considerable burden on patients and on society owing to its prevalence and …

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage
degradation but also synovial membrane inflammation, osteophyte formation and …

One of the most important issues facing cartilage tissue engineering is the inability to move
technologies into the clinic. Despite the multitude of current research in the field, it is known …

Articular cartilage is a physiologically non-self-renewing avascular tissue with a singular cell
type, the chondrocyte, which functions as the load-bearing surface of the arthrodial joint …

The role of native (not culture-expanded) joint-resident mesenchymal stem cells (MSCs) in
the repair of joint damage in osteoarthritis (OA) is poorly understood. MSCs differ from bone …

Mesenchymal stem cells (MSCs) are self-renewing precursor cells that can differentiate into
bone, fat, cartilage, and stromal cells of the bone marrow. Recent studies suggest that MSCs …

In spite of the advances in the knowledge of adult stem cells (ASCs) during the past few
years, their natural activities in vivo are still poorly understood. Mesenchymal stem cells …

Osteoarthritis (OA) represents a final and common pathway for all major traumatic insults to
synovial joints. OA is the most common form of degenerative joint disease and a major …

Mesenchymal stem/stromal cells (MSC) are typically used to generate bone tissue by a
process resembling intramembranous ossification, ie, by direct osteoblastic differentiation …

In many adult tissues, mesenchymal stem cells (MSCs) are closely associated with
perivascular niches and coexpress many markers in common with pericytes. The ability of …