Hyperpolarized magnetic resonance allows for noninvasive measurements of biochemical
reactions in vivo. Although this technique provides a unique tool for assaying enzymatic …

Dissolution dynamic nuclear polarization (d-DNP) is a versatile method to enhance nuclear
magnetic resonance (NMR) spectroscopy. It boosts signal intensities by four to five orders of …

Hyperpolarization produces nuclear spin polarization that is several orders of magnitude
larger than that achieved at thermal equilibrium thus providing extraordinary contrast and …

Due to its ability to enhance the signal of a single NMR scan by several orders of magnitude,
solid-to-liquid state dynamic nuclear polarization (DNP) appears well suited for the analysis …

Fluorine NMR spectroscopy is widely used for detection of protein–ligand interactions in
drug discovery because of the simplicity of fluorine spectra combined with a relatively high …

The development of biocompatible hyperpolarized media is a crucial step towards
application of hyperpolarization in vivo. This article describes the achievement of 1 …

Sensitivity of detection is one of the most limiting aspects when applying NMR spectroscopy
to current problems in the molecular sciences. A number of hyperpolarization methods exist …

The use of dissolution dynamic nuclear polarization (d‐DNP) offers substantially increased
signals in liquid‐state NMR spectroscopy. A challenge in realizing this potential lies in the …

Nuclear magnetic resonance (NMR) spectroscopy is a broadly used analytical method with
major applications in chemistry, biochemistry and medicine. Key applications include …

Hyperpolarization is an emerging method in magnetic resonance imaging that allows
nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six …