Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …

Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

Although obesity is associated with numerous diseases, the risks of disease may depend on
metabolic health. Associations between the gut microbiota, obesity, and metabolic syndrome …

Nonalcoholic fatty liver disease (NAFLD) is leading chronic liver syndrome worldwide. Gut
microbiota dysbiosis significantly contributes to the pathogenesis and severity of NAFLD …

The prevalence of overweight, obesity, type 2 diabetes, metabolic syndrome and steatotic
liver disease is rapidly increasing worldwide with a huge economic burden in terms of …

Objective We aimed to characterise the liver tissue bacterial metataxonomic signature in two
independent cohorts of patients with biopsy-proven non-alcoholic fatty liver disease …

Non-alcoholic fatty liver disease (NAFLD) is currently related to a heavy socioeconomic
burden and increased incidence. Since obesity is the most prevalent risk factor for NAFLD …

Fatty liver disease is the most common liver disease in the world. Its connection with the gut
microbiome has been known for at least 80 y, but this association remains mostly unstudied …

The microbiota–gut–liver axis has emerged as an important player in developing
nonalcoholic steatohepatitis (NASH), a type of nonalcoholic fatty liver disease (NAFLD) …

Our previous study showed that apple polyphenol extract (APE) ameliorated high-fat diet-
induced hepatic steatosis in C57BL/6 mice by targeting the LKB1/AMPK pathway; to …