Background There remains uncertainty about the impact of menopausal hormone therapy
(MHT) on women's health. A systematic, comprehensive assessment of the effects on …

Women spend approximately one-third of their lives with menopause, which occurs around
50 years of age. It is now appreciated that several important metabolic and cardiovascular …

For several decades, the role of hormone-replacement therapy (HRT) has been debated.
Early observational data on HRT showed many benefits, including a reduction in coronary …

Menopause is an aging process and an important time equivalent to one-third of a woman's
lifetime. Menopause significantly increases the risk of cardiometabolic diseases, such as …

Objective To investigate the long term effect of hormone replacement therapy on
cardiovascular outcomes in recently postmenopausal women. Design Open label …

Recent reports estimate that 0.6% of adults in the United States, or approximately 1.4 million
persons, identify as transgender. Despite gains in rights and media attention, the reality is …

Survivors of stroke and transient ischaemic attacks are at risk of a recurrent stroke, which is
often more severe and disabling than the index event. Optimum secondary prevention of …

Objective This study evaluated the short-and long-term cardiovascular-and cancer-related
morbidities during cross-sex hormone therapy in a large sample of trans persons. Subjects …

Introduction Long-term effects and side effects of cross-sex hormone treatment in
transsexual persons are not well known. Aim The aim of this study is to describe the effects …

BACKGROUND: Observational studies, including recent large cohort studies that were
unavailable for prior meta-analysis, have suggested an association between migraine …