Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating
adaptive immune responses. The functions of DCs were originally obscured by their overlap …

The hepatic immune system is constantly exposed to a massive load of harmless dietary and
commensal antigens, to which it must remain tolerant. Immune tolerance in the liver is …

Classical dendritic cells (cDCs), monocytes, and plasmacytoid DCs (pDCs) arise from a
common bone marrow precursor (macrophage and DC progenitors [MDPs]) and express …

Natural killer (NK) cells are important effector cells in the control of infections. The cellular
and molecular signals required for NK cell activation in vivo remain poorly defined. By using …

We examine the role of dendritic cells subsets in immunity to peripheral infections, with
emphasis on the differences in the regulation of primary and secondary T cell responses to …

In recent years, the essential role of bi-directional cross-talk between natural killer (NK) and
dendritic cells (DC) during immune responses has been clearly elucidated. In particular, this …

Natural killer (NK) cells are bone marrow–derived granular lymphocytes that have a key role
in immune defense against viral and bacterial infections and malignancies. NK cells are …

Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) have co-evolved with humans for
thousands of years and are present at a high prevalence in the population worldwide. HSV …

Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …

Conventional dendritic cells (cDCs) play an essential role in host immunity by initiating
adaptive T cell responses and by serving as innate immune sensors. Although both innate …