Recent advances in intranasal liposomes for drug, gene, and vaccine delivery
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
Prolactin and oxytocin: potential targets for migraine treatment
AK Szewczyk, S Ulutas, T Aktürk, L Al-Hassany… - The Journal of …, 2023 - Springer
Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully
understood. Besides the role of inflammatory mediators that interact with the …
understood. Besides the role of inflammatory mediators that interact with the …
Nose-to-brain delivery of therapeutic peptides as nasal aerosols
Central nervous system (CNS) disorders, such as psychiatric disorders, neurodegeneration,
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …
Effects of intranasal administration of oxytocin and vasopressin on social cognition and potential routes and mechanisms of action
S Yao, KM Kendrick - Pharmaceutics, 2022 - mdpi.com
Acute and chronic administration of intranasal oxytocin and vasopressin have been
extensively utilized in both animal models and human preclinical and clinical studies over …
extensively utilized in both animal models and human preclinical and clinical studies over …
Oxytocin improves intracerebral hemorrhage outcomes by suppressing neuronal pyroptosis and mitochondrial fission
M Yang, S Deng, J Jiang, M Tian, L Xiao, Y Gong - Stroke, 2023 - Am Heart Assoc
BACKGROUND: Intracerebral hemorrhage (ICH) causes severe sensorimotor dysfunction
and cognitive decline which are aggravated by secondary brain injury, yet there are no …
and cognitive decline which are aggravated by secondary brain injury, yet there are no …
[HTML][HTML] A paraventricular hypothalamic nucleus input to ventral of lateral septal nucleus controls chronic visceral pain
Irritable bowel syndrome is a functional gastrointestinal disorder characterized by chronic
visceral pain with complex etiology and difficult treatment. Accumulated evidence has …
visceral pain with complex etiology and difficult treatment. Accumulated evidence has …
Affective touch in the context of development, oxytocin signaling, and autism
Touch represents one of our most important senses throughout life and particularly in the
context of our social and emotional experiences. In this review, we draw on research on …
context of our social and emotional experiences. In this review, we draw on research on …
Advances and challenges in intranasal delivery of antipsychotic agents targeting the central nervous system
Treatment of central nervous system (CNS) disorders is challenging using conventional
delivery strategies and routes of administration because of the presence of the blood–brain …
delivery strategies and routes of administration because of the presence of the blood–brain …
Impact of magnesium on oxytocin receptor function
Simple Summary What is already known: Mg2+ levels modulate the affinity of oxytocin
receptors for oxytocin in vitro, low serum Mg2+ is correlated with migraine headache onset …
receptors for oxytocin in vitro, low serum Mg2+ is correlated with migraine headache onset …
Potential treatment targets for migraine: emerging options and future prospects
Migraine is a leading cause of disability worldwide. Despite the recent approval of several
calcitonin gene-related peptide-targeted therapies, many people with migraine do not …
calcitonin gene-related peptide-targeted therapies, many people with migraine do not …