MicroRNAs add a new dimension to cardiovascular disease

EM Small, RJA Frost, EN Olson - Circulation, 2010 - Am Heart Assoc
Cardiovascular disease is the predominant cause of human morbidity and mortality in
developed countries. Thus, extraordinary effort has been devoted to determining the …

Function of microRNA‐375 and microRNA‐124a in pancreas and brain

NN Baroukh, E Van Obberghen - The FEBS journal, 2009 - Wiley Online Library
In recent years, our understanding of how gene regulatory networks control cell physiology
has improved dramatically. Studies have demonstrated that transcription is regulated not …

[HTML][HTML] LncRNA TTN-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis

D Fu, C Lu, X Qu, P Li, K Chen, L Shan, X Zhu - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Aim: To explore the mechanism by which long non-coding RNA (lncRNA) TTN-AS1
regulates osteosarcoma cell apoptosis and drug resistance via the microRNA miR-134 …

Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs

C Voellenkle, J Van Rooij, A Guffanti, E Brini… - Rna, 2012 - rnajournal.cshlp.org
In order to understand the role of microRNAs (miRNAs) in vascular physiopathology, we
took advantage of deep-sequencing techniques to accurately and comprehensively profile …

MatureBayes: A Probabilistic Algorithm for Identifying the Mature miRNA within Novel Precursors

K Gkirtzou, I Tsamardinos, P Tsakalides, P Poirazi - PloS one, 2010 - journals.plos.org
Background MicroRNAs (miRNAs) are small, single stranded RNAs with a key role in post-
transcriptional regulation of thousands of genes across numerous species. While several …

MicroRNA targeting

H Ghanbarian, MT Yıldız, Y Tutar - miRNomics: MicroRNA Biology and …, 2022 - Springer
MicroRNAs (miRNAs) are small noncoding elements that play essential roles in the
posttranscriptional regulation of biochemical processes. miRNAs recognize and target …

Clinical significance and prognostic value of microRNA expression signatures in hepatocellular carcinoma

R Wei, GL Huang, MY Zhang, BK Li, HZ Zhang… - Clinical Cancer …, 2013 - AACR
Purpose: MicroRNAs (miRNAs) play important roles in the development and progression of
cancer. The aim of this study is to identify miRNA expression signatures in hepatocellular …

MiR-129-5p inhibits liver cancer growth by targeting calcium calmodulin-dependent protein kinase IV (CAMK4)

Z Li, J Lu, G Zeng, J Pang, X Zheng, J Feng… - Cell Death & …, 2019 - nature.com
This study was designed to investigate the mechanism by which miR-129-5p affects the
biological function of liver cancer cells. The expression levels of miR-129–5p in liver cancer …

Advancement in machine learning: A strategic lookout from cancer identification to treatment

M Bhatt, P Shende - Archives of Computational Methods in Engineering, 2023 - Springer
Abstract Machine learning is an established data interpretation tool for the development of
processing, extracting and extrapolating evocative results from complex data sets. Data …

Identification and characterization of microRNA in the dairy goat (Capra hircus) mammary gland by Solexa deep-sequencing technology

Z Ji, G Wang, Z Xie, C Zhang, J Wang - Molecular biology reports, 2012 - Springer
Abstract microRNAs (miRNAs) perform critical roles in various biological and metabolic
processes by regulating gene expression at the post-transcriptional level. To investigate the …