Alphaherpesvirus genomics: past, present and future

CV Kuny, ML Szpara - Current issues in molecular biology, 2021 - mdpi.com
Alphaherpesviruses, as large double-stranded DNA viruses, were long considered to be
genetically stable and to exist in a homogeneous state. Recently, the proliferation of high …

Embracing Complexity: What Novel Sequencing Methods Are Teaching Us About Herpesvirus Genomic Diversity

A Ortigas-Vasquez, M Szpara - Annual Review of Virology, 2024 - annualreviews.org
The arrival of novel sequencing technologies throughout the past two decades has led to a
paradigm shift in our understanding of herpesvirus genomic diversity. Previously …

Dermatitis during spaceflight associated with HSV-1 reactivation

SK Mehta, ML Szpara, BV Rooney, DM Diak… - Viruses, 2022 - mdpi.com
Human alpha herpesviruses herpes simplex virus (HSV-1) and varicella zoster virus (VZV)
establish latency in various cranial nerve ganglia and often reactivate in response to stress …

A holistic perspective on herpes simplex virus (HSV) ecology and evolution

MM Rathbun, ML Szpara - Advances in virus research, 2021 - Elsevier
Herpes simplex viruses (HSV) cause chronic infection in humans that are characterized by
periodic episodes of mucosal shedding and ulcerative disease. HSV causes millions of …

Complete and Prolonged Inhibition of Herpes Simplex Virus Type 1 Infection In Vitro by CRISPR/Cas9 and CRISPR/CasX Systems

DS Karpov, NA Demidova, KA Kulagin… - International Journal of …, 2022 - mdpi.com
Almost all people become infected with herpes viruses, including herpes simplex virus type
1 (HSV-1), during their lifetime. Typically, these viruses persist in a latent form that is …

[HTML][HTML] Comparison of herpes simplex virus 1 genomic diversity between adult sexual transmission partners with genital infection

MM Rathbun, MM Shipley, CD Bowen, S Selke… - PLoS …, 2022 - journals.plos.org
Herpes simplex virus (HSV) causes chronic infection in the human host, characterized by
self-limited episodes of mucosal shedding and lesional disease, with latent infection of …

Comparative analysis of multiple consensus genomes of the same strain of Marek's disease virus reveals intrastrain variation

A Ortigas-Vasquez, U Pandey, DW Renner… - Virus …, 2024 - academic.oup.com
Current strategies to understand the molecular basis of Marek's disease virus (MDV)
virulence primarily consist of cataloging divergent nucleotides between strains with different …