Surface functionalization of graphene‐based materials: Biological behavior, toxicology, and safe‐by‐design aspects

Z Guo, S Chakraborty, FA Monikh, DD Varsou… - Advanced …, 2021 - Wiley Online Library
The increasing exploitation of graphene‐based materials (GBMs) is driven by their unique
properties and structures, which ignite the imagination of scientists and engineers. At the …

Toxic effects and involved molecular pathways of nanoparticles on cells and subcellular organelles

N Liu, M Tang - Journal of Applied Toxicology, 2020 - Wiley Online Library
Owing to the increasing application of engineered nanoparticles (NPs), besides the
workplace, human beings are also exposed to NPs from nanoproducts through the skin …

Composition of intracellular protein corona around nanoparticles during internalization

C Wang, B Chen, M He, B Hu - ACS nano, 2021 - ACS Publications
It has been well established that the early-stage interactions of nanoparticles with cells are
governed by the extracellular protein corona. However, after entering into the cells, the …

The Janus of Protein Corona on nanoparticles for tumor targeting, immunotherapy and diagnosis

X Wang, W Zhang - Journal of Controlled Release, 2022 - Elsevier
The therapeutics based on nanoparticles (NPs) are considered as the promising strategy for
tumor detection and treatment. However, one of the most challenges is the adsorption of …

Machine learning in the identification, prediction and exploration of environmental toxicology: Challenges and perspectives

X Wu, Q Zhou, L Mu, X Hu - Journal of Hazardous Materials, 2022 - Elsevier
Over the past few decades, data-driven machine learning (ML) has distinguished itself from
hypothesis-driven studies and has recently received much attention in environmental …

Surface charge influences protein corona, cell uptake and biological effects of carbon dots

Y Arezki, F Delalande, C Schaeffer-Reiss, S Cianférani… - Nanoscale, 2022 - pubs.rsc.org
Carbon dots are emerging nanoparticles (NPs) with tremendous applications, especially in
the biomedical field. Herein is reported the first quantitative proteomic analysis of the protein …

Interactions of Graphene Oxide and Few-Layer Graphene with the Blood–Brain Barrier

V Castagnola, L Deleye, A Podestà, E Jaho… - Nano Letters, 2023 - ACS Publications
Thanks to their biocompatibility and high cargo capability, graphene-based materials
(GRMs) might represent an ideal brain delivery system. The capability of GRMs to reach the …

Graphene Oxide Nanosheets Toxicity in Mice Is Dependent on Protein Corona Composition and Host Immunity

Y Li, KC Mei, R Liam-Or, JTW Wang, FN Faruqu… - ACS …, 2024 - ACS Publications
Two-dimension graphene oxide (GO) nanosheets with high and low serum protein binding
profiles (high/low hard-bound protein corona/HChigh/low) are used in this study as model …

Dopamine receptor-mediated binding and cellular uptake of polydopamine-coated nanoparticles

Y Liu, CKK Choi, H Hong, Y Xiao, ML Kwok, H Liu… - ACS …, 2021 - ACS Publications
Polydopamine (PDA)-coated nanoparticles (NPs) are emerging carriers of therapeutic
agents for nanomedicine applications due to their biocompatibility and abundant entry to …

Soluble Nanographene C222: Synthesis and Applications for Synergistic Photodynamic/Photothermal Therapy

XH Ma, X Gao, JY Chen, M Cao, Q Dai… - Journal of the …, 2024 - ACS Publications
Nanographene C222, which consists of a planar graphenic plane containing 222 carbon
atoms, holds the record as the largest planar nanographene synthesized to date. However …